Z-VEID-FMK

Application: Functional Studies (Func), Cell Culture (CC)

Catalog no.: ABIN412081

Additional Information

Immunogen: Sequence: Z-Val-Glu(OMe)-Ile-Asp(OME)-FMK

Description: A synthetic peptide that irreversibly inhibits activity of VEID-dependent caspases (e.g., caspase-6). The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies.

Molecular Weight: 652.0

Application Details

Application Notes: We recommend using 2-10 μ M for inhibiting caspase activity in cell culture. The optimal doses may vary for different cells and culture conditions.

Purity: One spot by TLC

Buffer: 1 mg (or 5 mg) lyophilized powder

Storage: Reconstitution: Reconstitute in DMSO (20 mM)

Restrictions: For Research Use only

Publications

Product: Ariazi, Cunliffe, Lewis-Wambi et al.: "Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 47, pp. 18879-86, 2011 (PubMed).