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Perifosine (KRX-0401)

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Cell Culture (CC), Functional Studies (Func)
Pubmed 1 reference available
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Quantity 25 mg
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Availability Will be delivered in 2 to 3 Business Days
Characteristics Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.
Purity 99,00 %
Molecular Weight 462.66 Da
CAS-No 157716-52-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture.
Storage -20 °C
Expiry Date 24 months
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 image for Perifosine (KRX-0401) (ABIN412181) Perifosine (KRX-0401)
Product cited in: Maddigan, Truitt, Arsenault et al.: "EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5983-94, 2011 (PubMed).

Catalog No. ABIN412181
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