Akt Inhibitor

Details for Product No. ABIN412306
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Functional Studies (Func), Cell Culture (CC), Blocking Antibody (Inhibition)
Pubmed 2 references available
Quantity 1 mg
Shipping to United States ( )
Availability Please contact our customer support.
Characteristics Potent inhibitor of Akt (PKB) (IC50 = 2 µM). Weak inhibitor of phosphatidylinositol 3-kinase (PI3-K) (IC50 = 83 µM). Has been shown to inhibit the growth of the following cancer cell lines: HeLa (IC50 = 2.5 µM), HT-29 (IC50 = 10 µM), MCF-7 (IC50 = 1.2 µM), and PC-3 (IC50 = 2.0 µM).
Purity 98,00 %
Molecular Weight 578.8 Da
Restrictions For Research Use only
Format Solid
Reconstitution Solubility: Soluble in DMSO
Handling Advice Protect from air and moisture.
Storage -20 °C
Expiry Date 12 months
Supplier Images
Image no. 1 for Akt Inhibitor (ABIN412306) Akt Inhibitor
Product cited in: Xiang, Yin, Li et al.: "Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase." in: American journal of respiratory cell and molecular biology, Vol. 44, Issue 3, pp. 333-40, 2011 (PubMed).

Fan, Li, Levy et al.: "Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 10, pp. 6573-80, 2007 (PubMed).

Catalog No. ABIN412306
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)