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Caspase-1 Inhibitor Z-YVAD-FMK
Functional Studies (Func), Enzyme Activity Assay (EAA)
|8 references available|
|Price||132.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||Sequence: Z-Tyr-Val-Ala-Asp-FMK (FMK, fluoromethyl ketone)|
|Description||A synthetic peptide that irreversibly inhibits ICE (interleukin-1 β converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability.|
|Application Notes||We recommend using 1000-5000X dilutions for inhibiting caspase-1 activity in Jurkat cell culture (e.g., Add 1 μ l to 1-5 ml of culture medium). The optimal doses may vary for different cells and culture conditions.|
|Purity||>99% by HPLC analysis|
|Buffer||100 μ l Z-YVAD-FMK (2 mM) in DMSO|
|Storage||Store at –20 o C. SHELF LIFE: 1 year under proper storage conditions|
|Restrictions||For Research Use only|
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