Propidium Iodide

Details for Product No. ABIN412371
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Application
Functional Studies (Func), Enzyme Activity Assay (EAA)
Pubmed 21 references available
Quantity 1 mL
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Molecular Weight 668.39 Da
CAS-No 25535-16-4
Comment

Propidium Iodide (PI) binds to double-stranded DNA, but it can only cross the plasma membrane of nonviable cells. When viewed using a fluorescence microscope with a rhodamine filter, cells that have lost membrane integrity will show red PI staining throughout the nuclei. For analysis by flow cytometry, the PI staining can be monitored in FL2 channel.

Restrictions For Research Use only
Format Liquid
Handling Advice Protect from light and moisture.
Storage 4 °C
Expiry Date 12 months
Supplier Images
Propidium Iodide Propidium Iodide
Product cited in: Yamamoto, Obana, Yee et al.: "SP10 infectivity is aborted after bacteriophage SP10 infection induces nonA transcription on the prophage SPβ region of the Bacillus subtilis genome." in: Journal of bacteriology, Vol. 196, Issue 3, pp. 693-706, 2014 (PubMed).

Kar, Quesada: "A numerical simulation approach to studying anterior cruciate ligament strains and internal forces among young recreational women performing valgus inducing stop-jump activities." in: Annals of biomedical engineering, Vol. 40, Issue 8, pp. 1679-91, 2012 (PubMed).

Galvan, Foreman, Zeng et al.: "Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 3716-23, 2012 (PubMed).

Fens, van Wijk, Andringa et al.: "A role for activated endothelial cells in red blood cell clearance: implications for vasopathology." in: Haematologica, Vol. 97, Issue 4, pp. 500-8, 2012 (PubMed).

Tanaka, Jin, Lee et al.: "Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death." in: American journal of respiratory cell and molecular biology, Vol. 46, Issue 4, pp. 507-14, 2012 (PubMed).

Dondeti, Wubbenhorst, Lal et al.: "Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets." in: Cancer research, Vol. 72, Issue 1, pp. 112-21, 2012 (PubMed).

Corcoran, Contino, Deshpande et al.: "STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis." in: Cancer research, Vol. 71, Issue 14, pp. 5020-9, 2011 (PubMed).

Li, Xu, Wasserloos et al.: "Cytoprotective effects of albumin, nitrosated or reduced, in cultured rat pulmonary vascular cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 4, pp. L526-33, 2011 (PubMed).

Mao, Cao, Wood et al.: "A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway." in: Blood, Vol. 117, Issue 6, pp. 1986-97, 2011 (PubMed).

Mirza, Teo, Upcroft et al.: "A rapid, high-throughput viability assay for Blastocystis spp. reveals metronidazole resistance and extensive subtype-dependent variations in drug susceptibilities." in: Antimicrobial agents and chemotherapy, Vol. 55, Issue 2, pp. 637-48, 2011 (PubMed).

Shaw, Henderson, Flynn et al.: "Characterization of novel diaryl oxazole-based compounds as potential agents to treat pancreatic cancer." in: The Journal of pharmacology and experimental therapeutics, Vol. 331, Issue 2, pp. 636-47, 2009 (PubMed).

Snyder, Reynolds, Hollingsworth et al.: "Clara cells attenuate the inflammatory response through regulation of macrophage behavior." in: American journal of respiratory cell and molecular biology, Vol. 42, Issue 2, pp. 161-71, 2010 (PubMed).

Liao, Tsai, Wang et al.: "Modular patterning of structure and function of the striatum by retinoid receptor signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 18, pp. 6765-70, 2008 (PubMed).

Mitsuhashi, Endo, Obara et al.: "Ex vivo simulation of the action of antileukemia drugs by measuring apoptosis-related mRNA in blood." in: Clinical chemistry, Vol. 54, Issue 4, pp. 673-81, 2008 (PubMed).

Wang, Yang, Su et al.: "Enhanced antitumor effect of combined triptolide and ionizing radiation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 16, pp. 4891-9, 2007 (PubMed).

Fukushima, Matsuzawa, Kress et al.: "Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 15, pp. 6371-6, 2007 (PubMed).

Jiang, Kurnikov, Belikova et al.: "Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides." in: The Journal of pharmacology and experimental therapeutics, Vol. 320, Issue 3, pp. 1050-60, 2007 (PubMed).

Evans, Xu, Sirisawad et al.: "Motexafin gadolinium-induced cell death correlates with heme oxygenase-1 expression and inhibition of P450 reductase-dependent activities." in: Molecular pharmacology, Vol. 71, Issue 1, pp. 193-200, 2006 (PubMed).

Altmann, Pich, Ruiss et al.: "Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 38, pp. 14188-93, 2006 (PubMed).

Yanamandra, Colaco, Parquet et al.: "Tipifarnib and bortezomib are synergistic and overcome cell adhesion-mediated drug resistance in multiple myeloma and acute myeloid leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 2, pp. 591-9, 2006 (PubMed).

Medarova, Bonner-Weir, Lipes et al.: "Imaging beta-cell death with a near-infrared probe." in: Diabetes, Vol. 54, Issue 6, pp. 1780-8, 2005 (PubMed).

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Catalog No. ABIN412371
104.50 $
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Quantity
Price
1 mL
104.50 $

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