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Caspase-8 Inhibitor Z-IETD-FMK
Functional Studies (Func), Enzyme Activity Assay (EAA)
|10 references available|
|Quantity||20 ul (10 mM)|
|Price||132.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||Sequence: Z-Ile-Glu-Thr-Asp-FMK (FMK, fluoromethyl ketone)|
|Description||A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability.|
|Application Notes||We recommend using 5000X dilutions for inhibiting caspase-8 activity in Jurkat cell culture (e.g., Add 1 l to 5 ml of culture medium). The optimal doses may vary for different cells and culture conditions.|
|Purity||>99% by HPLC analysis.|
|Buffer||20 l Z-IETD-FMK (10 mM) in DMSO|
|Storage||Store at –20 o C. SHELF LIFE: 1 year under proper storage conditions|
|Restrictions||For Research Use only|
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