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5-Aza-2'-deoxycytidine

Catalog no. ABIN629024
Quantity 50 mg
Price 355.00 $   Plus shipping costs $35.00
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Additional Information

Description An epigenetic modifier. Decitabine is an analogue of the nucleoside 2’-deoxycytidine. It is believed to exert its antineoplastic effects after phosphorylation and direct incorporation into DNA and inhibition of DNA methyltransferase, causing hypomethylation of DNA and cellular differentiation or apoptosis. DNA hypomethylation is achieved at concentrations below those required to significantly inhibit DNA synthesis, which may promote restoration of function to genes associated with control of cellular differentiation and proliferation.

Application Details

Purity >=98% by HPLC
Storage Long term Storage: -20°C. Shipping condition: gel pack. Shelf Life: 24 months.
Research Area Kinases/Phosphatases
Restrictions For Research Use only