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17-AAG

Catalog no. ABIN629061
Quantity 5 mg
Price 470.00 $   Plus shipping costs $35.00
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Additional Information

Description A semi-synthetic derivative of Geldanamycin (Cat. No. 1564-1,5) that displays greater stability and lower in vivo toxicity compared to Geldanamycin. Binds to Heat shock protein 90 (Hsp90) (EC50 = 7.2 µM) in a manner similar to geldanamycin. Exhibits 100-fold higher affinity for tumor-derived Hsp90 over normal cells. Also inhibits Akt activation and HER2 expression in tumor cells.

Application Details

Purity >=98% by HPLC
Storage Long term Storage: -20°C. Shipping condition: gel pack. Shelf Life: 24 months.
Research Area Kinases/Phosphatases
Restrictions For Research Use only