Browse our Kininogen 1 Proteins (KNG1)

Full name:
Kininogen 1 Proteins (KNG1)
On are 40 Kininogen 1 (KNG1) Proteins from 11 different suppliers available. Additionally we are shipping Kininogen 1 Antibodies (169) and Kininogen 1 Kits (86) and many more products for this protein. A total of 342 Kininogen 1 products are currently listed.
BDK, BK, fb64g01, IHRP, kininogen, KINKG, KINKH, KINT1G, Kng, Kng1, Kng1_v1, KNG2, Kngk, Kngt, Kngt1, Kng_v1, Map1, Tkg, TKG6, wu:fb64g01, zgc:103569
list all proteins Gene Name GeneID UniProt
KNG1 3827 P01042
KNG1 16644 O08677
KNG1 24903  

Show all synonyms

Kininogen 1 Proteins (KNG1) by Origin

Select your origin of interest

Top referenced Kininogen 1 Proteins

  1. Human KNG1 Protein expressed in HEK-293 Cells - ABIN2181445 : Aron, Hertzeanu, Fisman, Frank, Kellermann: Correlation between arrhythmias and abnormal systolic blood pressure response to exercise in mitral valve prolapse patients. in Giornale italiano di cardiologia 1986 (PubMed)
    Show all 3 references for 2181445

More Proteins for Kininogen 1 Interaction Partners

Pig (Porcine) Kininogen 1 (KNG1) interaction partners

  1. Promoter of ITIH4 major acute phase protein has been isolated, cloned, and proven functional by response to an inflammatory stimulus (interleukin-6 (show IL6 Proteins)) in human Hep3B cells. (inter-alpha-trypsin heavy chain 4; ITIH4 (show ITIH4 Proteins))

Human Kininogen 1 (KNG1) interaction partners

  1. Three loci showed robust, replicating association with circulating FXI (show F11 Proteins) levels: KNG1 (rs710446, P-value = 2.07 x 10-302), F11 (show F11 Proteins) (rs4253417, P-value = 2.86 x 10-193), and a novel association in GCKR (show GCKR Proteins) (rs780094, P-value = 3.56 x10-09), here for the first time implicated in FXI (show F11 Proteins) regulation. The two first SNPs (rs710446 and rs4253417) also associated with partial thromboplastin (show F3 Proteins) time

  2. findings show that the KNG1 locus plays a central role as a genetic determinant of the entire coagulation pathway and thrombus/clot (show TXNDC17 Proteins) formation

  3. Urinary KNG1 and RBP4 clearly respond to AKI. Additionally, RBP4 could predict recovery by monitoring this protein levels over time after AKI, as RBP4 reflects patient's normalization earlier than sCr values do.

  4. KNG1 rs710446/ rs2304456 SNPs are not related to the incidence of Alzheimer's disease in a Hunan Han Chinese population.

  5. Low urine KNG1 expression is associated with clear cell renal cell carcinoma (show MOK Proteins).

  6. The results of this study supported the association of the epistatic interactions of ALOX5AP (show ALOX5AP Proteins), THBD (show THBD Proteins), and KNG1 and present novel evidence for the main effect of KNG1 gene on IS susceptibility.

  7. Bradykinin stimulates pro-contractile signalling mechanisms in human myometrial cells and arrestin (show SAG Proteins) proteins play key roles in their regulation.

  8. 2 genetic loci (kininogen 1 and kallikrein (show KLK4 Proteins) B) influencing key components of the RAAS, consistent with the close interrelation between the kallikrein (show KLK4 Proteins)-kinin system and the RAAS.

  9. Measuring plasma levels of cleaved HK may be a sensitive mean of assessing disease severity in HAE-C1-INH (show SERPING1 Proteins) patients.

  10. The antimicrobial protein kininogen evolved adaptively in mammals and human populations.

Mouse (Murine) Kininogen 1 (KNG1) interaction partners

  1. uPAR (show PLAUR Proteins) mediates efferocytosis through high molecular weight kininogen interaction with phosphatidylserine on apoptotic cells

  2. mice deficient in KNG showed less severe blood-brain barrier damage and edema formation, and the local inflammatory response was reduced compared with controls.

  3. Domain 5 of kininogen was identified as an anti-adhesive component with a potent anti-inflammatory action in a peritonitis mouse model.

  4. His-Gly-Lys (show LYZ Proteins) motif and lysine residue (Lys487) play essential roles in inhibition of cell adhesion and invasion in vitro and in prevention of metastasis of cancer cells in vivo

  5. mKng1 is responsible for production of plasma kininogen

Cow (Bovine) Kininogen 1 (KNG1) interaction partners

  1. Bradykinin, together with its precursor and tissue kallikrein (show KLK1 Proteins), is continuously released into the vasculature of the isolated, perfused, lactating bovine udder.

  2. Bradykini stimulates endothelial cell fatty acid oxidation by calmodulin-dependent kinase kinase -dependent activation of AMP-activated protein kinase (AMPK (show PRKAA2 Proteins))

Kininogen 1 (KNG1) Protein Profile

Protein Summary

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Kininogen 1 (KNG1)

  • kininogen 1 (kng1)
  • kininogen 1 (KNG1)
  • inter-alpha-trypsin inhibitor heavy chain family, member 4 (ITIH4)
  • kininogen (LOC100101602)
  • kininogen 1 (Kng1)
  • kininogen 1-like 1 (Kng1l1)
  • kininogen 2 (Kng2)
  • BDK protein
  • BK protein
  • fb64g01 protein
  • IHRP protein
  • kininogen protein
  • KINKG protein
  • KINKH protein
  • KINT1G protein
  • Kng protein
  • Kng1 protein
  • Kng1_v1 protein
  • KNG2 protein
  • Kngk protein
  • Kngt protein
  • Kngt1 protein
  • Kng_v1 protein
  • Map1 protein
  • Tkg protein
  • TKG6 protein
  • wu:fb64g01 protein
  • zgc:103569 protein

Protein level used designations for Kininogen 1 Proteins (KNG1)

kininogen-1 , kininogen 1 , kininogen-1-like , ITI heavy chain H4 , ITI-HC4 , MAP , inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) , inter-alpha-inhibitor heavy chain 4 , inter-alpha-trypsin inhibitor family heavy chain-related protein , inter-alpha-trypsin inhibitor heavy chain H4 , major acute phase protein , HMWK , alpha-2-thiol proteinase inhibitor , bradykinin , fitzgerald factor , high molecular weight kininogen , williams-Fitzgerald-Flaujeac factor , H-kininigen , L-kininogen , kininogen I , kininogen II , kininogen-2 , thiol proteinase inhibitor , K-kininogen, differential splicing leads to HMW Kngk , LMW T-kininogen I , T-kininogen 1 , T-kininogen I , alpha-1-MAP , kininogen 1, variant 1 , thiostatin , low molecular weight kininogen , T-kininogen 2 , T-kininogen II , low molecular weight (LMW) T-kininogen II , major acute phase protein (alpha-1-MAP) , K-kininogen

449808 Danio rerio
460916 Pan troglodytes
494833 Xenopus laevis
100038066 Xenopus (Silurana) tropicalis
100068133 Equus caballus
100405422 Callithrix jacchus
100597381 Nomascus leucogenys
396799 Sus scrofa
100101602 Oryctolagus cuniculus
3827 Homo sapiens
16644 Mus musculus
280833 Bos taurus
478666 Canis lupus familiaris
24903 Rattus norvegicus
396568 Sus scrofa
288001 Rattus norvegicus
25087 Rattus norvegicus
424957 Gallus gallus
Selected quality suppliers for Kininogen 1 Proteins (KNG1)
Did you look for something else?