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NOS3 gene SNP rs2070744 is significantly associated with hypoxic-ischemic encephalopathy susceptibility and symptom expression in Chinese Han population
Shear stress regulates endothelial cell function through SR-B1 (show SCARB1 Proteins)-eNOS (show NOS3 Proteins) signaling pathway.
eNOS (show NOS3 Proteins) T-786C polymorphism is significantly associated with arteriosclerotic parameters accompanied with age and gender differences, possibly involving antioxidative and/or endothelial signaling other than inflammatory signaling.
Association of endothelial nitric oxide synthase (eNOS (show NOS3 Proteins)) gene G894T polymorphism with hypertension risk and complications.
NOS3 gene SNPs are associated with risk of metabolic syndrome.
Data indicate that transfected mouse arginase-1 (show ARG1 Proteins) (Arg-I) promotes endothelial senescence and inflammatory responses through eNOS (show NOS3 Proteins)-uncoupling in human umbilical vein endothelial cells (HUVEC cells).
These findings point to a role for NOS3 polymorphisms in coronary artery disease (CAD) in the Chinese Han population, and may be useful for future investigations on the pathogenesis of CAD.
Ghrelin (show GHRL Proteins) pretreatment attenuated LPS (show IRF6 Proteins)- or palmitic acid-induced hepatocyte apoptosis, which may least partly via inhibition of mitogen-activated protein kinases (MAPKs)/iNOS (show NOS2 Proteins) and restoration of Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins) pathways
Our results demonstrated that GRP94 (show HSP90B1 Proteins) is a key molecule in Hepatocellular carcinoma (HCC (show FAM126A Proteins)) progression that modulates the AKT (show AKT1 Proteins) pathway and eNOS (show NOS3 Proteins) levels
eNOS (show NOS3 Proteins)-T786C and PAI-1 (show SERPINE1 Proteins)(4G/5G) are important polymorphisms in developing Buerger's disease
NANOS3 mutation is one possible cause of primary ovarian insufficiency.
Study suggests that Nanos3-3'UTR has an essential role in translational control in embryo.
Report distinct posttranscriptional regulations in primordial germ cells soon after their specification, for which RNA-binding proteins such as NANOS3 would play critical functions.
cloning and functional analyses of nanos2 (show NANOS2 Proteins) and nanos3; demonstrated an evolutionarily conserved function of nanos proteins in germ cell development [nanos2 (show NANOS2 Proteins)] [nanos3]
eNOS (show NOS3 Proteins) is the main isoform influencing the initiation of caerulein-induced AP. eNOS (show NOS3 Proteins)-derived NO exerts a protective effect through actions on nonacinar cell types, most likely endothelial cells, to produce greater pancreatic microvascular blood flow.
Potential role of Nanos3 in maintaining the undifferentiated spermatogonia population is reported.
Results suggest that Nanos3 maintains the germ cell lineage by suppressing both Bax (show BAX Proteins)-dependent and Bax (show BAX Proteins)-independent apoptotic pathways.
detection of the germ cell-specific proteins Nanos2 (show NANOS2 Proteins) and Nanos3 as markers of spermatogonia has enabled the clear dissection of complex populations of these cells as Nanos2 (show NANOS2 Proteins) was recently shown to be involved in the maintenance of stem cells
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
nanos homolog 3
, nanos homolog 3 (Drosophila)
, NOS type III
, constitutive NOS
, endothelial NOS
, nitric oxide synthase, endothelial
, endothelial nitric oxide synthase 3