Browse our CD109 Proteins (CD109)

Full name:
CD109 Molecule Proteins (CD109)
On www.antibodies-online.com are 7 CD109 Molecule (CD109) Proteins from 4 different suppliers available. Additionally we are shipping CD109 Antibodies (131) and CD109 Kits (32) and many more products for this protein. A total of 176 CD109 products are currently listed.
Synonyms:
9930012E15Rik, AI480638, CD109, CPAMD7, D11S833E, GARP, RP11-525G3.1
list all proteins Gene Name GeneID UniProt
CD109 135228 Q6YHK3
CD109 363104  
CD109 235505 Q8R422

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CD109 Proteins (CD109) by Origin

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More Proteins for CD109 Interaction Partners

Mouse (Murine) CD109 Molecule (CD109) interaction partners

  1. platelet and endothelial GARP (show LRRC32 Proteins) are not important in hemostasis and thrombosis in mice

  2. Small-scale in vivo screening identified several genes, including Cd109, that encode novel pro-metastatic factors. We uncovered signaling mediated by Janus kinases (Jaks) and the transcription factor Stat3 (show STAT3 Proteins) as a critical, pharmacologically targetable effector of CD109-driven lung cancer metastasis

  3. CD109 differentially regulates TGF-beta (show TGFB1 Proteins)-induced ALK1 (show ACVRL1 Proteins)-Smad1 (show SMAD1 Proteins)/5 versus ALK5 (show TGFBR1 Proteins)-Smad2 (show SMAD2 Proteins)/3 pathways, leading to decreased extracellular matrix production in the skin; epidermal CD109 expression regulates dermal function through a paracrine mechanism

  4. the GARP (show LRRC32 Proteins)/LTGF-beta1 complex on Treg cells is a major source of TGF-beta1 (show TGFB1 Proteins) needed for induction of pTreg cells during the process of oral tolerance.

  5. GP96 (show HSP90B1 Proteins) serves as an essential chaperone for the cell-surface protein (show CD28 Proteins) glycoprotein A repetitions predominant (GARP (show LRRC32 Proteins)), which is a docking receptor for latent membrane-associated TGF-beta (show TGFB1 Proteins) (mLTGF-beta).

  6. CD109 decreases extracellular matrix production and fibrotic responses during hypoxic wound healing

  7. CD109 is present in serum as a soluble form, and suggest its potential as a novel tumor marker in patients with cancers that express CD109.

  8. CD109 might be an important regulator of osteoclastogenesis.

  9. findings demonstrate that CD109 overexpression in the epidermis reduces inflammation and granulation tissue area and improves collagen organization in vivo.

  10. Induction of both Th17-producing cells and Tregs is caused preferentially by Tregs expressing the latent TGF-beta1 (show TGFB1 Proteins)/GARP (show LRRC32 Proteins) complex on their cell surface rather than by secreted latent TGF-beta1 (show TGFB1 Proteins).

Human CD109 Molecule (CD109) interaction partners

  1. The CD109 protein was up-regulated in hepatocellular carcinoma tissue compared with adjacent noncancerous tissue. CD109 shRNA knockdown delayed the G1-S phase transition, abrogated cell proliferation, and increased cell apoptosis. Furthermore, CD109 impaired TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins) signaling through control of p-smad2 (show SMAD2 Proteins).

  2. CD109 is a putative biomarker for identifying a high-risk group among DLBCL patients.

  3. The most common HPA (show HPSE Proteins) genotypes among Saudis were HPA-1 (show HPSE Proteins) a + b- (75%), HPA-2 a + b- (62%), HPA-3 a + b- (51.5%), HPA (show HPSE Proteins)-4 a + b- (99%), HPA-5 (show ITGA2 Proteins) a + b- (76.5%), HPA (show HPSE Proteins)-6 a + b- (100%) and HPA (show HPSE Proteins)-15 a + b + (50%). The prevalent allele among the HPA (show HPSE Proteins) systems was (a), except in the HPA (show HPSE Proteins)-15 system where the (b) allele was found in 52% of the subjects.

  4. Expression levels of CD109 was reduced significantly in psoriasis. Lower expression of CD109 and TGF-beta (show TGFB1 Proteins) RI was highly correlated with higher expression of Smad7 (show SMAD7 Proteins) and Ki67 (show MKI67 Proteins), suggesting that CD109 may induce the pathogenesis of psoriasis through Smad7 (show SMAD7 Proteins)-mediated degradation of TGF-beta (show TGFB1 Proteins) RI.

  5. sCD109 can bind TGF-beta (show TGFB1 Proteins), inhibit TGF-beta (show TGFB1 Proteins) binding to its receptors and decrease TGF-beta (show TGFB1 Proteins) signalling and TGF-beta (show TGFB1 Proteins)-induced cellular responses.

  6. These findings indicate that CD109 is an exosomal protein and that the C-terminal region of CD109 is required for its presence in the exosome.

  7. CD109 may be a potential pathology marker for gallbladder squamous cell/adenosquamous carcinomas.

  8. CD109 is specifically expressed in endothelial cells of cutaneous cavernous haemangioma.

  9. The results suggest that circulating endothelial cells express CD109 and represent a rare population of circulating tumor endothelial cells, that play a potentially useful prognostic role in patients with glioblastoma.

  10. CD109 overexpression was significantly associated with surgical stage, distant metastasis, and poor prognosis in myxofibrosarcoma.

CD109 Protein Profile

Protein Summary

This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.

Alternative names and synonyms associated with CD109

  • CD109 molecule (CD109)
  • leucine rich repeat containing 32 (LRRC32)
  • CD109 molecule (Cd109)
  • CD109 molecule (cd109)
  • CD109 antigen (Cd109)
  • 9930012E15Rik protein
  • AI480638 protein
  • CD109 protein
  • CPAMD7 protein
  • D11S833E protein
  • GARP protein
  • RP11-525G3.1 protein

Protein level used designations for CD109 Molecule Proteins (CD109)

150 kDa TGF-beta-1-binding protein , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7 , CD109 antigen , Gov platelet alloantigens , activated T-cell marker CD109 , p180 , platelet-specific Gov antigen , r150 , garpin , glycoprotein A repetitions predominant , leucine-rich repeat-containing protein 32 , CD109 molecule , CD109 antigen-like , GPI-anchored alpha 2 macroglobulin-related protein , GPI-anchored alpha-2 macroglobulin-related protein

GENE ID SPECIES
135228 Homo sapiens
2615 Homo sapiens
363104 Rattus norvegicus
421862 Gallus gallus
462825 Pan troglodytes
474970 Canis lupus familiaris
534043 Bos taurus
569058 Danio rerio
100068163 Equus caballus
100385557 Callithrix jacchus
100471342 Ailuropoda melanoleuca
100486953 Xenopus (Silurana) tropicalis
235505 Mus musculus
100155478 Sus scrofa
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