Browse our Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins (ITGAX)

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Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins (ITGAX)
On are 7 Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Proteins from 3 different suppliers available. Additionally we are shipping Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Antibodies (643) and Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Kits (1) and many more products for this protein. A total of 653 Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) products are currently listed.
AI449405, CD11C, Cr4, Itgax, N418, RGD1561123, SLEB6
list all proteins Gene Name GeneID UniProt
ITGAX 16411 Q9QXH4
ITGAX 3687 P20702

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Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins (ITGAX) by Origin

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More Proteins for Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Interaction Partners

Mouse (Murine) Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

  1. this study shows that PU.1 functions as a positive regulator of CD11c gene expression by directly binding to the Itgax promoter and through transactivation of the Irf4 (show IRF4 Proteins) gene

  2. Murine CD11c+ T cells analyzed by flow cytometry display markers associated with non-conventional T cell subsets, including gammadelta T cells and invariant natural killer T (iNKT) cells.

  3. Data concluded that the ablation of CD11c(hi) dendritic cells provided a subsidiary impact on blood-brain barrier (BBB) integrity and the expression of tight junction/adhesion molecules, thereby leading to exacerbated Japanese encephalitis (JE) progression.

  4. CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23 (show IL23A Proteins).

  5. data demonstrate that CD11c(hi) DCs provide a critical and unexpected role to preserve the immune-privileged CNS in lethal neuroinflammation via regulating the differentiation, function, and trafficking of CD11b(+)Ly-6C(hi) monocytes.

  6. The generation of mouse line with Flip deficiency in cells that express cre under the CD11c promoter is reported.

  7. Probucol effectively retarded atherosclerosis at least partly through lipid-lowering and inhibiting immune maturation of CD11c dendritic cells in STZ-induced diabetic LDLR (show LDLR Proteins) mice.

  8. Dual function of PPARgamma (show PPARG Proteins) in CD11c+ cells ensures immune tolerance in the airways.

  9. CD11c-expressing B cells are located at the T cell/B cell border in spleen and are potent antigen-presenting cells.

  10. Our findings suggest that increased numbers of CD11c(+) macrophages and elevated levels of TNF-alpha (show TNF Proteins) and MMP-3 (show MMP3 Proteins) in AT and ST may explain the relationship between hyperlipidaemia and OA.

Human Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

  1. Circulating CD11c+ T cells were associated with the expression of multiple adhesion molecules in women, suggesting that these cells have high tissue homing potential. These data suggest that CD11c expression distinguishes a population of circulating T cells during bacterial infection with innate capacity and mucosal homing potential.

  2. CD8 (show CD8A Proteins)+ T cells of Behcet's disease patients exhibited increased CD11c expression levels, which may contribute to disease pathogenesis.

  3. High expression of CD11c decreased the risk of death and relapse, and may be regarded as an alternative indicator of favorable prognosis in patients with gastric cancer.

  4. the CD11c molecule possesses four different cellular patterns in the periprosthetic tissues.

  5. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Proteins)), factor H (show CFH Proteins)-receptors CD11b/CD18 (show ITGAM Proteins) and CD11c/CD18 (show ITGB2 Proteins).

  6. Data show that the percentage of CD11c positive antigen presenting cells (CD11c(+) APCs (show APCS Proteins)) in the peripheral blood of active pulmonary tuberculosis (APT) patients was much higher than that in the controls.

  7. Data suggest that blood neutrophils expressing CD11c antigen and EMR2 protein be considered as potential biomarkers for sepsis and systemic inflammatory response syndrome (SIRS), respectively.

  8. Modification of Levels of Adhesion Molecule (show NCAM1 Proteins) Expression of Human Innate Immune Cells by Glycopolymers of Marine Bacteria

  9. three of these five genes (CXCL14 (show CXCL14 Proteins), ITGAX, and LPCAT2 (show LPCAT2 Proteins)) harbored polymorphisms associated with aggressive disease development in a human GWAS cohort consisting of 1,172 prostate cancer patients.

  10. infiltration of MBP (show MBL2 Proteins)(+) and CD11c(+) innate immune cells show a significant association with phenotype and disease extent of non-asthmatic chronic rhinosinusitis

Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Protein Profile

Protein Summary

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Alternative names and synonyms associated with Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX)

  • integrin alpha X (Itgax)
  • integrin, alpha D (Itgad)
  • integrin, alpha X (Itgax)
  • integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX)
  • AI449405 protein
  • CD11C protein
  • Cr4 protein
  • Itgax protein
  • N418 protein
  • RGD1561123 protein
  • SLEB6 protein

Protein level used designations for ITGAX

CD11 antigen-like family member C , CD11C (p150) alpha polypeptide , complement receptor 4 , integrin aX , integrin alpha-X , leukocyte adhesion glycoprotein p150,95 alpha chain , leukocyte adhesion receptor p150,95 , integrin alpha X (Cd11c) , integrin alpha-D , integrin, alpha X (antigen CD11C (p150), alpha polypeptide) , leu M5, alpha subunit , leukocyte surface antigen p150,95, alpha subunit , myeloid membrane antigen, alpha subunit , p150 95 integrin alpha chain

16411 Mus musculus
64350 Rattus norvegicus
499271 Rattus norvegicus
3687 Homo sapiens
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