Browse our anti-ADAM8 (ADAM8) Antibodies

On www.antibodies-online.com are 115 ADAM Metallopeptidase Domain 8 (ADAM8) Antibodies from 20 different suppliers available. Additionally we are shipping ADAM8 Kits (40) and ADAM8 Proteins (11) and many more products for this protein. A total of 172 ADAM8 products are currently listed.
Synonyms:
ADAM8, CD156, CD156a, E430039A18Rik, MS2, reprolysin, RGD1566394, si:zc217g15.7, zgc:64059
list all antibodies Gene Name GeneID UniProt
ADAM8 101 P78325
ADAM8 11501 Q05910
ADAM8 309098  

Most Popular Reactivities for anti-ADAM8 (ADAM8) Antibodies

anti-Human ADAM8 Antibodies:

anti-Mouse (Murine) ADAM8 Antibodies:

anti-Rat (Rattus) ADAM8 Antibodies:

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More Antibodies against ADAM8 Interaction Partners

Human ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

  1. ADAM8 on leukocytes holds a proinflammatory function in acute lung inflammation by promoting alveolar leukocyte recruitment.

  2. miR (show MLXIP Antibodies)-720 is elevated in serum of patients with ADAM8-high TNBC and, in a group with other miRNAs downstream of ADAM8, holds promise as a biomarker for early detection of or treatment response of ADAM8-positive triple-negative breast cancer

  3. ADAM8 causes temozolomide resistance in glioblastoma cells by enhancing pAkt/PI3K, pERK1/2, and cleavage of CD44 and HGF R/c-met

  4. ADAM8 promotes GC cell proliferation and invasion, and its expression is positively correlated with poor survival, indicating that it might be a promising target in GC therapy

  5. ADAM8 expression is associated with increased migration and invasiveness of pancreatic ductal adenocarcinoma cells.

  6. ADAM8 and endostatin (show COL18A1 Antibodies) play a role in osteosarcoma progression.

  7. Data indicate that fibronectin fragments (FN-fs) are present in adult ntervertebral disc (IVD) from adult subjects, and ADAM-8, known to cleave FN, is present at the pericellular matrix of disc cells.

  8. Results show that ADAM8 is overexpressed in colorectal cancer and promotes cell growth.

  9. N-glycosylation is essential for processing, localization, stability, and activity of ADAM8.

  10. ADAM8 expression is increased in both severe asthma and COPD (show ARCN1 Antibodies) and associated with sputum total cell count and neutrophils. ADAM8 may facilitate neutrophil migration to the airways in severe asthma and COPD (show ARCN1 Antibodies).

Mouse (Murine) ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

  1. ADAM8 on leukocytes holds a proinflammatory function in acute lung inflammation by promoting alveolar leukocyte recruitment.

  2. The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice

  3. ADAM8 mediates an enhanced invasiveness of neutrophils into injured muscle fibers by the removal of their adhesiveness to blood vessels after infiltration into interstitial tissues.

  4. ADAM8 has anti-inflammatory activities during allergic airway inflammation in mice

  5. overexpression of PrP(C (show PRNP Antibodies)) led to up-regulation of ADAM8, suggesting that PrP(C (show PRNP Antibodies)) may regulate its own alpha-cleavage through modulating ADAM8 activity.

  6. ADAM-8 appears to favour allergen-induced acute airway inflammation by promoting dendritic cell recruitment and CCL11 (show CCL11 Antibodies) and CCL22 (show CCL22 Antibodies) production.

  7. ADAM8 knockout mice did not display a bone phenotype in vivo but they did not increase RANKL (show TNFSF11 Antibodies) production, OCL (show OCLN Antibodies) formation, or calvarial fibrosis in response to tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies)) in vivo.

  8. ADAM8 is involved in T cell maturation in the medulla but has a relatively minor impact on T cell development.

  9. The results of this study indicated an essential role for ADAM8 in modulating TNF-alpha (show TNF Antibodies) signaling in CNS diseases

  10. The study finds an increase in retinal re-vascularization but fewer neovascular tufts in the oxygen-induced retinopathy model and increased growth of heterotopically injected tumor cells in Adam8-/- mice compared with wild-type controls.

ADAM8 Antigen Profile

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with ADAM8

  • ADAM metallopeptidase domain 8 (ADAM8) antibody
  • a disintegrin and metalloproteinase domain 8 (LOC100304737) antibody
  • a disintegrin and metallopeptidase domain 8 (Adam8) antibody
  • tubulin, gamma complex associated protein 2 (Tubgcp2) antibody
  • a disintegrin and metalloproteinase domain 8a (adam8a) antibody
  • ADAM metallopeptidase domain 8 (Adam8) antibody
  • a disintegrin and metalloproteinase domain 8 (adam8) antibody
  • ADAM8 antibody
  • CD156 antibody
  • CD156a antibody
  • E430039A18Rik antibody
  • MS2 antibody
  • reprolysin antibody
  • RGD1566394 antibody
  • si:zc217g15.7 antibody
  • zgc:64059 antibody

Protein level used designations for ADAM8

a disintegrin and metalloproteinase domain 8 , cell surface antigen MS2 , disintegrin and metalloproteinase domain-containing protein 8 , human leukocyte differentiation antigen , ADAM 8 , a disintegrin and metalloprotease domain (ADAM) 8 , a disintegrin and metalloprotease domain 8 , macrophage cysteine-rich glycoprotein , gamma-tubulin complex component 2 , CD156a , metalloprotease , ADAM metallopeptidase domain 8 , a disintegrin and metallopeptidase domain 8 , disintegrin and metalloproteinase domain-containing protein 8-like

GENE ID SPECIES
101 Homo sapiens
100304737 Ictalurus punctatus
11501 Mus musculus
309098 Rattus norvegicus
368917 Danio rerio
423672 Gallus gallus
491699 Canis lupus familiaris
499285 Rattus norvegicus
519652 Bos taurus
100156146 Sus scrofa
100303713 Ictalurus punctatus
100393217 Callithrix jacchus
100428452 Macaca mulatta
100471554 Ailuropoda melanoleuca
100726804 Cavia porcellus
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