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Browse our IFI16 Proteins (IFI16)

Full name:
Interferon, gamma-Inducible Protein 16 Proteins (IFI16)
On are 7 Interferon, gamma-Inducible Protein 16 (IFI16) Proteins from 6 different suppliers available. Additionally we are shipping IFI16 Antibodies (88) and IFI16 Kits (22) and many more products for this protein. A total of 123 IFI16 products are currently listed.
Ifi16, IFNGIP1, p204, PYHIN2
list all proteins Gene Name GeneID UniProt
Mouse IFI16 IFI16 15951 P15092 , Q08619
IFI16 3428 Q16666

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IFI16 Proteins (IFI16) by Origin

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Mouse (Murine) Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

  1. p204 initiated innate antiviral responses in adipose cells, thereby modulating adipocyte function.

  2. cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection.

  3. The present study demonstrated that mouse Leydig cells had innate antiviral activities in response to viral DNA challenge through p204 activation.

  4. Data indicate that the transient expression of p204 in the early stage is indispensable for adipocyte differentiation. Disruption of p204 expression patterns at this stage leads to irreversible damage in fat formation.

  5. IFI16 exerts in vivo anti-tumoral activity by promoting apoptosis of tumor cells.

  6. This gene product interacts with the Tpr protein, a component of the nuclear pore complex.

  7. expression of p204 is activated by the cardiac Gata4 (show GATA4 Proteins), Nkx2.5 (show NKX2-5 Proteins), and Tbx5 (show TBX5 Proteins) proteins

  8. binding of Id1, Id2, or Id3 protein to the Gata4 and Nkx2.5 proteins inhibits the p204-induced differentiation of P19 cells to myocytes

  9. p204 synergizes with pRb (show PGR Proteins) in the stimulation of Cbfa1 (show RUNX2 Proteins)-dependent gene activation and osteoblast differentiation

  10. Ifi204 is a regulator of monocyte/macrophage differentiation and make possible a connection with other myeloid regulators [review]

Human Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

  1. Data show that NOD-like receptor signaling genes NOD2, PYCARD (show PYCARD Proteins), CARD6, and IFI16 are upregulated in psoriatic epidermis.

  2. By combining biochemical assays and single-molecule techniques, the authors show that the nuclear innate immune sensor IFI16 one-dimensionally tracks long stretches of exposed foreign dsDNA to assemble into supramolecular signaling platforms.

  3. High levels of circulating IFI16 in rheumatoid arthritis are more frequent in RF/anti-CCP (show CRYGD Proteins)-positive RA patients and significantly associated with pulmonary involvement.

  4. A significant upregulation of the PYHIN inflammasomes AIM2 (show AIM2 Proteins) and IFI16 in active inflammatory bowel disease versus controls was found.

  5. Results provide mechanistic insights into the regulation of IFI16 during HSV-1 infection and show interactions with ICP0 and PML (show PML Proteins)-containing ND10 bodies that can contribute to IFI16 antiviral functions.

  6. Studies of the dynamics of the response of PML (show PML Proteins) nuclear body components and IFI16 to invading herpes simplex virus 1 genomes demonstrated that human Daxx (hDaxx (show DAXX Proteins)) and IFI16 respond more rapidly than PML (show PML Proteins).

  7. These findings demonstrate that IFI16 plays a critical role in fms-like tyrosine kinase 1 (show FLT1 Proteins) and soluble endoglin (show ENG Proteins) production in human trophoblast cells.

  8. IFI16 sera concentration was directly correlated with disease duration and inversely correlated with age at diagnosis of Sjogren's syndrome.

  9. increased nuclear acetylation of IFI16 is a dynamic essential post-genome recognition event in the nucleus that is common to the IFI16-mediated innate responses of inflammasome induction and IFN-beta (show IFNB1 Proteins) production during herpesvirus infections

  10. BRCA1 is a constituent of the triggered IFI16-inflammasome and is translocated into the cytoplasm after genome recognition along with the IFI16-inflammasome

IFI16 Protein Profile

Protein Summary

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IFI16

  • interferon, gamma-inducible protein 16 (IFI16)
  • interferon activated gene 204 (Ifi204)
  • interferon, gamma-inducible protein 16 (Ifi16)
  • Ifi16 protein
  • IFNGIP1 protein
  • p204 protein
  • PYHIN2 protein

Protein level used designations for IFI16

interferon, gamma-inducible protein 16 , ifi-204 , interferon, gamma-inducible gene 204 , interferon-activable protein 204 , interferon-inducible protein p204 , gamma-interferon-inducible protein 16 , interferon-gamma induced protein IFI 16 , interferon-inducible myeloid differentiation transcriptional activator , interferon activated gene 203 , Gamma-interferon-inducible protein Ifi-16 , ifi-16

457424 Pan troglodytes
100607897 Nomascus leucogenys
15951 Mus musculus
3428 Homo sapiens
100718476 Cavia porcellus
100156073 Sus scrofa
100172051 Pongo abelii
506759 Bos taurus
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