Browse our anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) Antibodies

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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Antibodies (KLRK1)
On www.antibodies-online.com are 206 Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) Antibodies from 25 different suppliers available. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Proteins (21) and Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Kits (3) and many more products for this protein. A total of 238 Killer Cell Lectin-Like Receptor Subfamily K, Member 1 products are currently listed.
Synonyms:
CD314, D6H12S2489E, D12S2489E, KLR, KLRK1, NKG2-D, Nkg2d, Nkrp2
list all antibodies Gene Name GeneID UniProt
KLRK1 22914 P26718
KLRK1 27007 O54709
KLRK1 24934 O70215

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Top referenced anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Antibodies

  1. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898794 : Lee, Kang, Yoon, Jin, Song, Her, Kang, Hwang, Kang, Joo, Nam: Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain. in BMC cancer 2015 (PubMed)
    Show all 19 references for 4898794

  2. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN320264 : Das, Sugita, Brenner: Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 6 references for 320264

  3. Human Monoclonal KLRK1 Primary Antibody for FACS, IHC (fro) - ABIN120294 : Bauer, Groh, Wu, Steinle, Phillips, Lanier, Spies: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 6 references for 120294

  4. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898788 : Vossen, Matmati, Hertoghs, Baars, Gent, Leclercq, Hamann, Kuijpers, van Lier: CD27 defines phenotypically and functionally different human NK cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 6 references for 4898788

  5. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN120295 : Groh, Bruhl, El-Gabalawy, Nelson, Spies: Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 6 references for 120295

  6. Human Polyclonal KLRK1 Primary Antibody for IF (p), IHC (p) - ABIN730078 : Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers. in Archivum immunologiae et therapiae experimentalis 2014 (PubMed)
    Show all 3 references for 730078

  7. Human Monoclonal KLRK1 Primary Antibody for FACS, Func - ABIN260439 : Vitales-Noyola, Martínez-Martínez, Loyola-Rodríguez, Baranda, Niño-Moreno, González-Amaro: Quantitative and functional analysis of CD69(+) T regulatory lymphocytes in patients with periodontal disease. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 (PubMed)
    Show all 2 references for 260439

  8. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898792 : van Meijgaarden, Haks, Caccamo, Dieli, Ottenhoff, Joosten et al.: Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human ... in PLoS pathogens 2015 (PubMed)
    Show all 2 references for 4898792

  9. Human Polyclonal KLRK1 Primary Antibody for ELISA, WB - ABIN185435 : Hayakawa, Smyth: Innate immune recognition and suppression of tumors. in Advances in cancer research 2006 (PubMed)
    Show all 2 references for 185435

More Antibodies against Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. The interaction of Fas receptor (show FAS Antibodies) with FasL (show FASL Antibodies) leads to an activation of the Tag7 (show PGLYRP1 Antibodies)-Hsp70 (show HSP70 Antibodies) complex in the lymphocyte membrane fraction, and here FasL (show FASL Antibodies) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (show MICA Antibodies) stress ligand with the NKG2D receptor is necessary for the release of this cytotoxic complex

  2. Blockade of NKG2D on CD8 (show CD8A Antibodies)(+) T cells inhibited the migration over ligand-expressing endothelial cells. Intestinal induction of NKG2D ligands and ligand-induced down-regulation of NKG2D in Crohn's disease (CD) suggest that the NKG2D-ligand interaction may be involved in both the activation and recruitment of NKG2D(+) lymphocytes into the inflamed CD intestine.

  3. IDH (show IDH1 Antibodies) mutant glioma cells acquire resistance to natural killer cells through epigenetic silencing of NKG2D ligands ULBP1 (show ULBP1 Antibodies) and ULBP3 (show ULBP3 Antibodies)

  4. non-virally infected human T cells can express NKG2DL, with implications for stress surveillance by the large number of NKG2D-expressing NK cells sequestered in the liver.

  5. After PSK (show TAOK2 Antibodies) administration, INF (show GIF Antibodies)-g production in CD8 (show CD8A Antibodies)(+) T cells increased in mice with cells expressing neither Rae-1 (show RAE1 Antibodies) nor H60, but did not change in mice implanted with cells expressing both Rae-1 (show RAE1 Antibodies) and H60. We demonstrated that the expression of NKG2DLs affects tumor immunity and the efficacy of immuno therapy in tumor-bearing mouse model

  6. These results suggest the involvement of HIV-1 nef and human NKG2D-NKG2D ligand interactions in the enhanced susceptibility of HIV-1-infected cells from HIV elite controllers to antibody-dependent cellular cytotoxicity responses.

  7. Blocking the interaction of NKG2D with its ligands deleted the sensitizing effects of HCQ. In addition, we showed that HCQ did not affect the synthesis or degradation of ULBP4 (show RAET1E Antibodies), but induced the translocation of ULBP4 (show RAET1E Antibodies) from the cytoplasm to the cell membrane

  8. High NKG2D expression is associated with hepatocellular carcinoma.

  9. In the second trimester, functional markers of Decidual natural killer activation, i.e., angiogenic factor (show VEGFA Antibodies) production (e.g., vascular endothelial growth factor, interleukin-8 (show IL8 Antibodies), interferon-gamma (show IFNG Antibodies)), remained stable despite an increase in NKp80 (show KLRF1 Antibodies) or NKG2D surface expression.

  10. Our data showed that NKG2D receptor could be an independent favorable prognostic indicator for gastric cancer. Furthermore, decreased NKG2D expression might be the mechanism underlying immune evasion by tumors in gastric cancer.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. study demonstrates that the effect of NKG2D on B1a cell development occurs at a developmental stage that precedes the common lymphoid progenitor; findings reveal an unexpected new role for NKG2D in the regulation of B1a cell development

  2. Sirt6 (show SIRT6 Antibodies) binds to promoters of NKG2D ligand genes and regulates the H3K9 and H3K56 acetylation levels

  3. These results support the conclusion that svH1C mimics Neu5Ac-containing sequences and interacts with cell-surface receptor NKG2D, which contains a lectin-like domain

  4. These results indicate that, unlike in the pancreas, NKG2D-NKG2D ligand interaction does not play a critical role in obesity-induced inflammation in the adipose tissue.

  5. The results show that NK cells and the NKG2D receptor play a role in control of lymphomas, and that selection of NKG2D-ligand (MULT1 (show ULBP1 Antibodies)) loss mutants provides a mechanism for tumor escape.

  6. these data support a novel role for NKG2D expression by CD8 (show CD8A Antibodies)(+) T cells during allogeneic HSCT, which could be potentially therapeutically exploited to separate GVHD from GVT effects.

  7. NKG2D and NKG2DL are involved in allergen-induced activation of dendritic epidermal T cells and the NKG2D/NKG2DL pathway might be a potential target for treatment of contact hypersensitivity.

  8. Viral infection of cultured cells increased RAE-1 (show RAE1 Antibodies) expression, resulting in enhanced NK cell-mediated killing through NKG2D recognition.

  9. Activation through the NKG2D receptor leads to the differential activation of the NF-kappaB (show NFKB1 Antibodies) signaling pathway and potentially enhances the anti-tumor and anti-viral functions of effector CD8 (show CD8A Antibodies)(+) T cells.

  10. Desiccating stress-induced chemokine (show CCL1 Antibodies) expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 (show RAE1 Antibodies) and release of IFN-gamma (show IFNG Antibodies) in experimental dry eye.

Pig (Porcine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. The effect of Bacillus cereus on the stress response of enterocytes, including the expression of NKG2D, is reported.

Rhesus Monkey Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. Determined expressions of NKG2D in decidual natural killer cells in patients having spontaneous abortions.

Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) Antigen Profile

Antigen Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.

Alternative names and synonyms associated with Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)

  • killer cell lectin-like receptor subfamily K, member 1 (KLRK1) antibody
  • NKG2-D type II integral membrane protein-like (LOC100398970) antibody
  • killer cell lectin-like receptor subfamily K, member 1 (Klrk1) antibody
  • NKG2D protein (NKG2D) antibody
  • CD314 antibody
  • D6H12S2489E antibody
  • D12S2489E antibody
  • KLR antibody
  • KLRK1 antibody
  • NKG2-D antibody
  • Nkg2d antibody
  • Nkrp2 antibody

Protein level used designations for KLRK1

killer cell lectin-like receptor subfamily K, member 1 , NKG2-D type II integral membrane protein-like , NK cell receptor D , NKG2-D type II integral membrane protein , NKG2-D-activating NK receptor , natural killer cell group 2D , NK lectin-like receptor , NKLLR , NKR-P2, ortholog of human NKG2D , killer cell lectin-like receptor subfamily K member 1 , NKG2-D activating NK receptor

GENE ID SPECIES
611355 Canis lupus familiaris
100126736 Papio anubis
100398970 Callithrix jacchus
22914 Homo sapiens
27007 Mus musculus
24934 Rattus norvegicus
396737 Sus scrofa
450153 Pan troglodytes
574240 Macaca mulatta
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