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Browse our NOD2 (NOD2) ELISA Kits

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Nucleotide-Binding Oligomerization Domain Containing 2 ELISA Kits (NOD2)
On are 4 Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) ELISA Kits from 2 different suppliers available. Additionally we are shipping NOD2 Antibodies (151) and and many more products for this protein. A total of 165 NOD2 products are currently listed.
ACUG, BLAU, Card15, CD, CLR16.3, F830032C23Rik, IBD1, Nlrc2, NOD2B, PSORAS1
list all ELISA KIts Gene Name GeneID UniProt
NOD2 64127 Q9HC29
NOD2 257632  
Rat NOD2 NOD2 291912  

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Human Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. infant with severe IBD characterized by granulomatous colitis and severe perianal disease, we identified a homozygous variant of TRIM22 that affects the ability of its product to regulate NOD2.

  2. No correlation between the NOD2/CARD15 variants and clinical or laboratory findings was found in gouty arthritis

  3. NODs are functionally expressed in OSCC cells and can trigger innate immune responses. In addition, NOD2 agonist inhibited cell proliferation and induced apoptosis.

  4. Data show that NOD-like receptor signaling genes NOD2, PYCARD (show PYCARD ELISA Kits), CARD6 (show CARD6 ELISA Kits), and IFI16 (show IFI16 ELISA Kits) are upregulated in psoriatic epidermis.

  5. Protein expressions of NOD2 but not TLR2 (show TLR2 ELISA Kits) of basophils were significantly down-regulated in AD patients compared with controls

  6. NOD2 and NOD1 (show NOD1 ELISA Kits) polymorphisms were associated with an increased susceptibility to Guillain-Barre syndrome in a Northern Indian population.

  7. over-expression of NOD1 (show NOD1 ELISA Kits) and NOD2 may be involved in the pathogenesis of Vogt-Koyanagi-Harada (VKH) Syndrome syndrome.

  8. NOD2 Loss-of-Function Mutations are associated with Necrotizing Enterocolitis and Focal Intestinal Perforation.

  9. Increased Expression of NOD2 is associated with Inflammatory Bowel Disease.

  10. The genetic variants in the NOD2 is closely associated with leprosy is Chinese population.

Mouse (Murine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. This study signifies that NOD-2 and TLR-4 (show TLR4 ELISA Kits) exhibit synergism in invigorating the activity of dendritic cells.

  2. Deletion of the bacterial peptidoglycan sensor NOD2 had relatively minor effects on immune responses.

  3. Sertoli cells have a functional NALP3 (show NLRP3 ELISA Kits) inflammasome that modulates NOD1 (show NOD1 ELISA Kits) and pro-IL-1beta (show IL1B ELISA Kits) expression, while NOD2 inversely promoted IL-1beta (show IL1B ELISA Kits) expression.

  4. CD44 (show CD44 ELISA Kits), NOD2, and Fas (show FAS ELISA Kits) have distinct functions in regulating changes in trabecular and cortical bone indices during unloading.

  5. The results indicate that Nod1 (show NOD1 ELISA Kits) cooperates with Nod2 or TLRs to produce cytokines in macrophages in response to M. tuberculosis infection.

  6. Myocardial ischemia reperfusion injury markedly up-regulated NOD2 expression in heart tissue.

  7. A novel crosstalk between TLR4 (show TLR4 ELISA Kits)- and NOD2-mediated signaling in the regulation of intestinal inflammation

  8. Nod2-/- alveolar macrophages and blood neutrophils displayed a reduced capacity to internalize pneumococci in vitro.

  9. NOD1 (show NOD1 ELISA Kits) and NOD2, play a collaborative role in T cell activation by alloantigen and that their blockade in vitro can inhibit T cell responses.

  10. NOD2 and its downstream adaptor protein IPS-1 (show ISYNA1 ELISA Kits) have been found to be essential for LTB4 (show PTGR1 ELISA Kits)-mediated effects against IAV infection.

Cow (Bovine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.

  2. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.

  3. Genetic variation and putative regulatory regions in bovine CARD15.

  4. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.

NOD2 Antigen Profile

Antigen Summary

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Alternative names and synonyms associated with NOD2

  • caspase recruitment domain 15 protein (TTHERM_01951320) Elisa Kit
  • nucleotide-binding oligomerization domain containing 2 (NOD2) Elisa Kit
  • nucleotide-binding oligomerization domain containing 2 (Nod2) Elisa Kit
  • ACUG Elisa Kit
  • BLAU Elisa Kit
  • Card15 Elisa Kit
  • CD Elisa Kit
  • CLR16.3 Elisa Kit
  • F830032C23Rik Elisa Kit
  • IBD1 Elisa Kit
  • Nlrc2 Elisa Kit
  • NOD2B Elisa Kit
  • PSORAS1 Elisa Kit

Protein level used designations for NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2

7828465 Tetrahymena thermophila
64127 Homo sapiens
257632 Mus musculus
291912 Rattus norvegicus
444867 Bos taurus
454083 Pan troglodytes
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