AMPK Activator, D942

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Purpose A potent AMPK activator
Characteristics A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.
Purity ≥ 98 % by HPLC
Chemical Name 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid
Formula C₂₂H₂₁FO₄
Permeability Cell-permeable
Solubility DMSO (10 mg/ml)
Molecular Weight 368.4 g/mol
CAS-No 849727-81-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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