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Browse our anti-CRTC2 (CRTC2) Antibodies

Full name:
anti-CREB Regulated Transcription Coactivator 2 Antibodies (CRTC2)
On www.antibodies-online.com are 151 CREB Regulated Transcription Coactivator 2 (CRTC2) Antibodies from 21 different suppliers available. Additionally we are shipping CRTC2 Proteins (5) and many more products for this protein. A total of 170 CRTC2 products are currently listed.
Synonyms:
4632407F12Rik, CRTC2, mTORC2, RGD1308903, TORC-2, Torc2
list all antibodies Gene Name GeneID UniProt
CRTC2 200186 Q53ET0
CRTC2 74343 Q3U182
CRTC2 310615 Q3LRZ1

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Top referenced anti-CRTC2 Antibodies

  1. Human Polyclonal CRTC2 Primary Antibody for EIA, WB - ABIN493522 : Koo, Flechner, Qi, Zhang, Screaton, Jeffries, Hedrick, Xu, Boussouar, Brindle, Takemori, Montminy: The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. in Nature 2005 (PubMed)
    Show all 6 references for ABIN493522

  2. Human Polyclonal CRTC2 Primary Antibody for WB - ABIN658088 : Nakatsu, Sakoda, Kushiyama, Ono, Fujishiro, Horike, Yoneda, Ohno, Tsuchiya, Kamata, Tahara, Isobe, Nishimura, Katagiri, Oka, Fukushima, Takahashi, Kurihara, Uchida, Asano: Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN658088

  3. Human Monoclonal CRTC2 Primary Antibody for ICC, FACS - ABIN969067 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)
    Show all 3 references for ABIN969067

  4. Human Polyclonal CRTC2 Primary Antibody for IHC (p), WB - ABIN658242 : Kaizuka, Hara, Oshiro, Kikkawa, Yonezawa, Takehana, Iemura, Natsume, Mizushima: Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN658242

  5. Human Monoclonal CRTC2 Primary Antibody for EIA, FACS - ABIN1106840 : Peng, Xie, Lu, Fan, Wang: Synthesis, photoelectric properties and photocatalytic activity of the Fe2O3/TiO2 heterogeneous photocatalysts. in Physical chemistry chemical physics : PCCP 2010 (PubMed)
    Show all 2 references for ABIN1106840

  6. Human Polyclonal CRTC2 Primary Antibody for IF (p), IHC (p) - ABIN745988 : Tian, Zhao, Sun, Zhi, Cheng, Zhou, Hu: CRTC2 enhances HBV transcription and replication by inducing PGC1? expression. in Virology journal 2014 (PubMed)

More Antibodies against CRTC2 Interaction Partners

Human CREB Regulated Transcription Coactivator 2 (CRTC2) interaction partners

  1. Our results establish a role for CRTC2 as a lymphoma tumor suppressor gene

  2. In neuroblastoma (show ARHGEF16 Antibodies), transcription of HIF2A (show EPAS1 Antibodies) is strongly dependent on mTORC2.

  3. the high expression of CRTC2 and PROM1 may play an important role in the occurrence and hereditary, and also advance the potential pathways that integrate genetic variants in the development of NSCLC.

  4. The data from the current study demonstrated novel PROM1 and CRTC2 mutations, which could promote lung cancer development.

  5. These results clearly indicate that non-phosphorylated CRTC2 strongly enhances hepatitis b virus biosynthesis through inducing PGC1alpha expression.

  6. Phosphorylation of CRTC2 at its AMPK (show PRKAA1 Antibodies) target site, Ser (show SIGLEC1 Antibodies) 171, dictated its subcellular localization, and the activation of aromatase (show CYP19A1 Antibodies) PII in preadipocytes.

  7. CRTC2 enhances CREB (show CREB1 Antibodies) phosphorylation through an association with the protein arginine methyltransferase 5 (PRMT5 (show PRMT5 Antibodies)).

  8. we found that overexpressed RIOK2 formed a complex with RIOK1 (show RIOK1 Antibodies), mTor (show FRAP1 Antibodies), and mTor (show FRAP1 Antibodies)-complex-2(TORC2) components, and that overexpressed RIOK2 upregulated Akt (show AKT1 Antibodies) signaling and promoted tumorigenesis

  9. TGFbeta (show TGFB1 Antibodies)-stimulated Smad 3 (show SMAD3 Antibodies) acts as a key node to instill a feedback loop between deptor (show DEPTOR Antibodies) down-regulation and TORC1 (show CRTC1 Antibodies)/2 activation in driving mesangial cell hypertrophy

  10. Mechanism of CREB (show CREB1 Antibodies) recognition and coactivation by the CREB (show CREB1 Antibodies)-regulated transcriptional coactivator CRTC2

Mouse (Murine) CREB Regulated Transcription Coactivator 2 (CRTC2) interaction partners

  1. mTORC2 has a central role in IFNgamma signaling and type II IFN responses

  2. CRTC2 promotes Th17 cell differentiation via stimulation of IL-17A (show IL17A Antibodies) and IL-17F (show IL17F Antibodies) expression by binding to CREB (show CREB1 Antibodies) over both promoters. CRTC2-mutant mice have decreased Th17 cells, and they are protected from experimental autoimmune encephalitis.

  3. chronic increases in CRTC2 activity in the liver are indeed sufficient to promote hepatic insulin (show INS Antibodies) resistance and to disrupt glucose homeostasis

  4. cAMP, SIK (show SIK1 Antibodies) and CRTC mediate StAR expression through activation of individual StAR gene loci.

  5. our study demonstrates the existence of a direct crosstalk between mTORC2 and MST1 (show MST1 Antibodies) that is critical for cardiac cell survival and growth.

  6. RICTOR (show RICTOR Antibodies)/mTORC2 is important for interactions between vasculature, adipocytes, and brain to tune physiological outcomes, such as blood pressure and locomotor activity.

  7. CREB regulated transcription coactivator 2 (CRTC2) functions as a mediator of mTOR (show FRAP1 Antibodies) signalling to modulate COPII-dependent SREBP1 (show SREBF1 Antibodies) processing

  8. Our findings provide new insight into the role of mTORC2 in regulating dendritic cell function

  9. RICTOR (show RICTOR Antibodies) depletion on lifespan is independent of the role of hepatic mTORC2 in promoting glucose tolerance.

  10. mTORC2 activation is essential for keratinocyte survival, and inhibition of mTORC2 has value in chemoprevention by eliminating carcinogen-damaged cells during the early stages of tumorigenesis.

CRTC2 Antigen Profile

Antigen Summary

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.

Alternative names and synonyms associated with CRTC2

  • CREB regulated transcription coactivator 2 (CRTC2) antibody
  • CREB regulated transcription coactivator 2 (LOC100358960) antibody
  • CREB regulated transcription coactivator 2 (Crtc2) antibody
  • 4632407F12Rik antibody
  • CRTC2 antibody
  • mTORC2 antibody
  • RGD1308903 antibody
  • TORC-2 antibody
  • Torc2 antibody

Protein level used designations for CRTC2

CREB regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2-like , transducer of regulated cAMP response element-binding protein (CREB) 2 , TORC-2 , transducer of CREB protein 2 , transducer of regulated cAMP response element-binding protein 2

GENE ID SPECIES
612305 Canis lupus familiaris
715908 Macaca mulatta
100056571 Equus caballus
100151904 Sus scrofa
100358960 Oryctolagus cuniculus
100472270 Ailuropoda melanoleuca
100019951 Monodelphis domestica
100597840 Nomascus leucogenys
200186 Homo sapiens
74343 Mus musculus
310615 Rattus norvegicus
540959 Bos taurus
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