Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
nuclear localization of active eEF-2 depends upon its interaction with p53 (show TP53 ELISA Kits), as cells lacking p53 (show TP53 ELISA Kits) contain less active eEF-2 in the nuclear compartment
High serum eukaryotic elongation factor 2 level is associated with non-small cell lung cancer.
Results indicated that the eEF2 gene is overexpressed in the majority of several types of cancers and plays an oncogenic role in cancer cell growth.
The expression levels of three putative HA-regulated proteins (TALDO, ANXA1 (show ANXA1 ELISA Kits) and EF2) in control, H2O2-, HA- and HA/H2O2-treated OA chondrocytes were verified by Western blotting and the results indeed support the notion that HA acts in anti-oxidation
Data indicate that the accumulation of the cleaved C-terminal small fragment of eukaryotic elongation factor 2 (eEF2) in the nucleus, and C-terminal Src kinase (Csk (show CSK ELISA Kits)) could enhance the proteolytic cleavage of eEF2.
Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death.
A single amino acid substitution in eukaryotic elongation factor 2 co-segregates with the disease phenotype of spinocerebellar ataxia (show USP14 ELISA Kits) 26.
EEF2 phosphorylation by cyclin A (show CCNA2 ELISA Kits)-cyclin-dependent kinase 2 (CDK2 (show CDK2 ELISA Kits)) on a novel site, serine 595 (S595), directly regulates T56 phosphorylation by eEF2K (show EEF2K ELISA Kits).
Burn induces prolonged activation of eEF2K (show EEF2K ELISA Kits) and eEF2 in pediatric patients.
PHD2 (show EGLN1 ELISA Kits) modulated eEF2 activity and protein translation under acute hypoxia.
IL-6 (show IL6 ELISA Kits) induces the activation of the Stat3 (show STAT3 ELISA Kits) signaling and promotes the downmodulation of the p90RSK (show RPS6KA1 ELISA Kits)/eEF2 and mTOR (show FRAP1 ELISA Kits)/p70S6K (show RPS6KB1 ELISA Kits) axes, while it does not affect the activation of AKT (show AKT1 ELISA Kits).
AMPKalpha2 (show PRKAA2 ELISA Kits) controls cardiac p70S6K (show RPS6KB1 ELISA Kits) under normoxia and regulates eEF-2 but not the mTOR (show FRAP1 ELISA Kits)-p70S6K (show RPS6KB1 ELISA Kits) pathway during ischemia.
The MKK3 (show MAP2K3 ELISA Kits)/6-p38gamma (show MAPK12 ELISA Kits)/delta pathway mediated an inhibitory phosphorylation of eukaryotic elongation factor 2 (eEF2) kinase, which in turn promoted eEF2 activation (dephosphorylation) and subsequent TNF-alpha (show TNF ELISA Kits) elongation.
Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development
induced by basic fibroblast growth factor (show FGF2 ELISA Kits) via mitogen-activated protein kinase (show MAPK1 ELISA Kits)
eEF-2 is activated by both lithium and GSK-3, whereas, lithium treatment and inhibition of GSK-3 have opposing effects on eEF-2.
eEF-2 phosphorylation has a role in protein synthesis for memory consolidation
A mouse that was mutant for the gene, Dph4 (show DNAJC24 ELISA Kits), was identified.
exogenous ROS (show ROS1 ELISA Kits) inhibit mTOR (show FRAP1 ELISA Kits), eIF2alpha (show EIF2A ELISA Kits), and eEF2, mTOR (show FRAP1 ELISA Kits) and eEF2 were largely refractory to ROS (show ROS1 ELISA Kits) generated under moderate hypoxia (0.5% O(2)).
Eukaryotic elongation factor-2 (eEF2) may be a limiting factor in milk protein (show CSN2 ELISA Kits) synthesis (Review)
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
eukaryotic translation elongation factor 2
, elongation factor 2-like
, elongation factor 2
, polypeptidyl-tRNA translocase
, elongation factor-2