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anti-Mouse (Murine) Glycogen Synthase 2 Antibodies:
anti-Rat (Rattus) Glycogen Synthase 2 Antibodies:
anti-Human Glycogen Synthase 2 Antibodies:
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Chicken Polyclonal Glycogen Synthase 2 Primary Antibody for WB - ABIN2782340
Watanabe, Tomita, Shimizu, Sugawara, Yasumo, Koishi, Takahashi, Miyoshi, Nakamura, Izumi, Matsushita, Furukawa, Haruyama, Koga: A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. in Clinical pharmacology and therapeutics 2003
These data show that G6P-mediated activation of GYS2 plays a key role in controlling glycogen synthesis and hepatic glucose-G6P flux control and thus whole-body glucose homeostasis.
A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies Gys2 as novel candidate obesity genes.
Transgenic LGS mice showed enhanced glycogen (show GYS1 Antibodies) storage and an mproved glucose tolerance.
CLOCK regulates the circadian rhythms of hepatic glycogen (show GYS1 Antibodies) synthesis through transcriptional activation of Gys2.
The endogenous glycogen synthase in extracts from mouse liver bound specifically to SAPK2b/p38b (show MAPK11 Antibodies) & was phosphorylated at residues Ser644, Ser652, Thr718 and Ser724.
Mouse enzyme is a novel target of peroxisome proliferator-activated receptor (show PPARG Antibodies), which is in turn mediated by two response elements.
Sequencing of the GYS2 gene is more likely to be positive in patients with fasting ketotic hypoglycaemia and concomitant postprandial hyperglycaemia with hyperlactataemia.
The GYS2 gene is a new susceptibility gene that significantly affects the risk for ovary syndrome through obesity-related conditions.
GYS2 was expressed specifically in liver and subcutaneous adipose tissue
The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
glycogen [starch] synthase, liver
, glycogen synthase, liver
, Glycogen synthase 2 (liver)