On are 0 STE20-Related Kinase Adaptor alpha (STRADA) ELISA Kits from different suppliers available. Additionally we are shipping STRADA Antibodies (95) and STRADA Proteins (12) and many more products for this protein. A total of 116 STRADA products are currently listed.
2610019A05Rik, 6030402H20Rik, AI480680, E130112C09Rik, fj99g05, Lyk5, NY-BR-96, PMSE, Stlk, STRAD, wu:fj99g05, zgc:56109
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More ELISA Kits for STRADA Interaction Partners

Rabbit STE20-Related Kinase Adaptor alpha (STRADA) interaction partners

  1. SPAK (show STK39 ELISA Kits) is a powerful regulator of peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2 (show SLC15A2 ELISA Kits)

Human STE20-Related Kinase Adaptor alpha (STRADA) interaction partners

  1. aberrant nuclear accumulation of LKB1 (show STK11 ELISA Kits) caused by STRADalpha deficiency contributes to hyperactivation of mTORC1 signaling and disruption of neuronal lamination during corticogenesis

  2. Several novel splice isoforms of STRADalpha that differentially affect the kinase activity, complex assembly, subcellular localization of LKB1 (show STK11 ELISA Kits) and the activation of the LKB1 (show STK11 ELISA Kits)-dependent AMPK (show PRKAA1 ELISA Kits) pathway were discovered.

  3. study describes structure of the core heterotrimeric LKB1 (show STK11 ELISA Kits)-STRADalpha-MO25alpha (show CAB39 ELISA Kits) complex, revealing an unusual allosteric mechanism of LKB1 (show STK11 ELISA Kits) activation; structure also reveals how mutations in Peutz-Jeghers syndrome & sporadic cancers impair LKB1 (show STK11 ELISA Kits) function

  4. Identification and characterization of an LKB1 (show STK11 ELISA Kits)-specific adaptor protein and substrate, STRAD. Results imply that STRAD plays a key role in regulating the tumor suppressor activities of LKB1 (show STK11 ELISA Kits).

  5. identify a multifactored mechanism to control LKB1 (show STK11 ELISA Kits) localization, and they suggest that the STRADbeta-LKB1 (show STK11 ELISA Kits) complex might possess unique functions in the nucleus

  6. LKB1 (show STK11 ELISA Kits) deacetylation is regulated by SIRT1 (show SIRT1 ELISA Kits) and that this in turn influences its intracellular localization, association with STRAD, kinase activity, and ability to activate AMPK (show PRKAA1 ELISA Kits).

  7. STRADalpha.MO25alpha complexes containing LKB1 (show STK11 ELISA Kits) variants were equally effective at phosphorylating and activating AMPK (show PRKAA1 ELISA Kits), BRSK1 (show BRSK1 ELISA Kits), and BRSK2 (show BRSK2 ELISA Kits)

  8. These data define a brush border induction pathway downstream of the Lkb1 (show STK11 ELISA Kits)/Strad/Mo25 (show CAB39 ELISA Kits) polarization complex, yet separate from other polarity events.

  9. ATP and MO25alpha (show CAB39 ELISA Kits) cooperate to maintain STRADalpha in an "active" closed conformation required for LKB1 (show STK11 ELISA Kits) activation.

Mouse (Murine) STE20-Related Kinase Adaptor alpha (STRADA) interaction partners

  1. Quantitative PCR revealed significantly reduced LKB1 (show STK11 ELISA Kits), MO25alpha (show CAB39 ELISA Kits), and STRADbeta mRNA in LKB1 (show STK11 ELISA Kits)(-/-) muscle. These findings demonstrate that the LKB1 (show STK11 ELISA Kits)-MO25 (show CAB39 ELISA Kits)-STRAD complex is the principal AMPKK in skeletal muscle.

  2. aberrant nuclear accumulation of LKB1 (show STK11 ELISA Kits) caused by STRADalpha deficiency contributes to hyperactivation of mTORC1 signaling and disruption of neuronal lamination during corticogenesis

STRADA Antigen Profile

Antigen Summary

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Alternative names and synonyms associated with STRADA

  • STE20-related kinase adaptor alpha (STRADA) Elisa Kit
  • ste20-related kinase adaptor alpha (strada) Elisa Kit
  • STE20-related kinase adaptor alpha (strada) Elisa Kit
  • STE20-related kinase adaptor alpha (Strada) Elisa Kit
  • 2610019A05Rik Elisa Kit
  • 6030402H20Rik Elisa Kit
  • AI480680 Elisa Kit
  • E130112C09Rik Elisa Kit
  • fj99g05 Elisa Kit
  • Lyk5 Elisa Kit
  • NY-BR-96 Elisa Kit
  • PMSE Elisa Kit
  • Stlk Elisa Kit
  • STRAD Elisa Kit
  • wu:fj99g05 Elisa Kit
  • zgc:56109 Elisa Kit

Protein level used designations for STRADA

protein kinase LYK5 , STE20-related kinase adapter protein alpha , STE20-related kinase adaptor alpha , STE20-related kinase adapter protein alpha-like , STE20-like pseudokinase , STRAD alpha , serologically defined breast cancer antigen NY-BR-96 , STE20-related adapter protein

739133 Pan troglodytes
334550 Danio rerio
493513 Xenopus (Silurana) tropicalis
609377 Canis lupus familiaris
100026111 Monodelphis domestica
100064638 Equus caballus
100302087 Ovis aries
100348595 Oryctolagus cuniculus
100391088 Callithrix jacchus
100472786 Ailuropoda melanoleuca
100563472 Anolis carolinensis
100588298 Nomascus leucogenys
92335 Homo sapiens
515024 Bos taurus
303605 Rattus norvegicus
72149 Mus musculus
419957 Gallus gallus
100172403 Pongo abelii
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