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Details for Product No. ABIN1001852

B-Cell Receptor-Associated Protein 29 (BCAP29) antibody

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Antigen
Synonyms Bap29, AW208404, BAP29, DKFZp459M024
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN1001852
Quantity 100 µg
Price
514.01 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 7 Business Days
Immunogen Rabbit polyclol BAP29 antibody was raised against a 17 amino acid peptide from near the center of human Bap29 (Genbank accession No. NP_001008405). Bap29 antibody is specific for isoform a of Bap29.
Isotype IgG
Purification Affinity chromatography purified via peptide column.
Alternative Name B-cell Receptor Associated Protein 29
Background Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
Application Notes Bap29 antibody can be used for the detection of Bap29 by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user.) Antibody can also be used for ELISA and might be suited for other applications not tested so far.
Restrictions For Research Use only
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Handling Advice Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months
Product cited in: Kim, Adachi, Nielsen et al.: "Two new proteins preferentially associated with membrane immunoglobulin D." in: The EMBO journal, Vol. 13, Issue 16, pp. 3793-800, 1994 (PubMed).

Ng, Nguyen, Kwan et al.: "p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum." in: The Journal of cell biology, Vol. 139, Issue 2, pp. 327-38, 1997 (PubMed).

Schamel, Kuppig, Becker et al.: "A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 17, pp. 9861-6, 2003 (PubMed).

Alternatives for antigen "B-Cell Receptor-Associated Protein 29 (BCAP29)", type "Antibodies"
Hosts (39), (6)
Reactivities (41), (24), (22)
Applications (45), (19), (10), (8), (6), (4), (1), (1)
Epitopes (11), (9), (6), (4), (2), (1), (1), (1), (1)
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