Flu Hemagglutinin 2 (Influenza H5N1) antibody

Details for Product No. ABIN1002326
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Reactivity
Virus
Host
Goat
Clonality
Polyclonal
Application
ELISA
Pubmed 3 references available
Catalog no. ABIN1002326
Quantity 100 µg
Price
514.01 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 7 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen AFHA-2 antibody was raised against a synthetic peptide corresponding to 12 amino acids near the amino terminus of the Hemagglutinin protein Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
Isotype IgG
Purification Affinity chromatography purified via peptide column.
Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.
Application Notes Avian Influenza Hemagglutinin 2 antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 µg/ml. (Optimal dilution should be determined by user.) Other applications are pending.
Restrictions For Research Use only
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Handling Advice Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months
Product cited in: Shortridge, Zhou, Guan et al.: "Characterization of avian H5N1 influenza viruses from poultry in Hong Kong." in: Virology, Vol. 252, Issue 2, pp. 331-42, 1999 (PubMed).

Alexander: "A review of avian influenza in different bird species." in: Veterinary microbiology, Vol. 74, Issue 1-2, pp. 3-13, 2000 (PubMed).

Thompson, Shay, Weintraub et al.: "Mortality associated with influenza and respiratory syncytial virus in the United States." in: JAMA : the journal of the American Medical Association, Vol. 289, Issue 2, pp. 179-86, 2003 (PubMed).

back to top