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Details for Product No. ABIN1003029

Podoplanin (PDPN) antibody

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Antigen
Synonyms T1A, GP36, GP40, Gp38, OTS8, T1A-2, AGGRUS, HT1A-1, PA2.26, OTS-8, RANDAM-2, T1-alpha, T1a, T1alpha, E11, RTI40, PDPN
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN1003029
Quantity 100 µg
Price
514.01 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 7 Business Days
Immunogen Membrane protein fraction of isolated human glomeruli
Clone 4D5aE5E6
Isotype IgG1 kappa
Specificity The antibody is human specific
Purification Protein G affinity chromatography
Alternative Name Podoplanin
Background Monoclonals were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen. The mouse IgG1 antibody (#4D5aE5E6) from hybridomas was purified from cell culture supernatant by Protein G chromatography.
Application Notes Immunohistochemistry: Cryo sections (acetone fixed) Paraffin sections (after autoclave or microwave treatment in 0.01 M citrate buffer, pH 6.0). Recommended working concentration is 0.5 µg/ml. Optimal dilutions should be determined by each laboratory for each application.
Restrictions For Research Use only
Format Liquid
Buffer PBS (pH 6.0) w/o preservative
Preservative Without preservative
Handling Advice Reconstituted antibody can also be aliquotted and stored at –20°C to –70°C for at least 6 months without detectable loss of activity.
Storage -20 °C
Product cited in: Breiteneder-Geleff, Matsui, Soleiman et al.: "Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis." in: The American journal of pathology, Vol. 151, Issue 4, pp. 1141-52, 1997 (PubMed).

Breiteneder-Geleff, Soleiman, Kowalski et al.: "Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium." in: The American journal of pathology, Vol. 154, Issue 2, pp. 385-94, 1999 (PubMed).

Kriehuber, Breiteneder-Geleff, Groeger et al.: "Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages." in: The Journal of experimental medicine, Vol. 194, Issue 6, pp. 797-808, 2001 (PubMed).

Kerjaschki, Huttary, Raab et al.: "Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants." in: Nature medicine, Vol. 12, Issue 2, pp. 230-4, 2006 (PubMed).

Alternatives for antigen "Podoplanin (PDPN)", type "Antibodies"
Hosts (67), (53), (15), (13), (5), (4), (1)
Reactivities (111), (43), (19), (2)
Applications (93), (51), (44), (34), (34), (28), (21), (20), (15), (11), (6), (3), (1), (1)
Conjugates (9), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (12), (7), (6), (6), (3), (1), (1), (1)
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