CD105 (Endoglin / TGF-Beta1/3 Receptor) antibody

Details for Product No. ABIN1003125
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Antigen
Synonyms CD105, AI528660, AI662476, S-endoglin, END, HHT1, ORW1
Reactivity
Human
(224), (94), (35), (34), (25), (13), (13), (6), (1)
Host
Rabbit
(143), (117), (40), (2), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(31), (26), (19), (9), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
(187), (162), (63), (57), (46), (42), (38), (29), (22), (15), (7), (7), (5), (4), (4), (1), (1)
Pubmed 6 references available
Catalog no. ABIN1003125
Quantity 100 µg
Price
441.41 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 7 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombint human soluble CD105/Endoglin
Isotype IgG
Purification Protein A affinity chromatography (+ His tag depleted)
Alternative Name sCD105 (Endoglin)
Background Produced from sera of rabbits immunized with highly pure recombinant human soluble CD105/Endoglin produced in insect cells. The recombinant soluble CD105/Endoglin consists of amino acid 26 (Glu) to 586 (Leu) and is fused to a C-terminal His-tag (6xHis).
Application Notes ELISA: Use at 1-15 µg/ml. Western Analysis: Use at a concentration of 1-2 µg/ml with the appropriate secondary reagents. FACS analysis and cell sorting: Use at 2-5 µg/ml together with the appropriate secondary reagents. Immunohistochemistry: Not investigated so far. Optimal dilutions should be determined by each laboratory for each application.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from PBS (pH 7.4) w/o preservative
Preservative Without preservative
Handling Advice The lyophilized IgG is stable at 4°C for at least six months and for greater than a year when kept at –20°C.
Storage -20 °C
Product cited in: Cheifetz, Bellón, Calés et al.: "Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells." in: The Journal of biological chemistry, Vol. 267, Issue 27, pp. 19027-30, 1992 (PubMed).

McAllister, Grogg, Johnson et al.: "Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1." in: Nature genetics, Vol. 8, Issue 4, pp. 345-51, 1995 (PubMed).

Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, 1999 (PubMed).

Arthur, Ure, Smith et al.: "Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development." in: Developmental biology, Vol. 217, Issue 1, pp. 42-53, 2000 (PubMed).

Fonsatti, Del Vecchio, Altomonte et al.: "Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies." in: Journal of cellular physiology, Vol. 188, Issue 1, pp. 1-7, 2001 (PubMed).

Parker, Goldring, Philip: "Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGFbeta receptor independent manner." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 18, Issue 2, pp. 289-302, 2003 (PubMed).

Hosts (143), (117), (40), (2), (2)
Reactivities (224), (94), (35), (34), (25), (13), (13), (6), (1)
Applications (187), (162), (63), (57), (46), (42), (38), (29), (22), (15), (7), (7), (5), (4), (4), (1), (1)
Conjugates (31), (26), (19), (9), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (9), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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