GAD65 antibody (AA 4-22)

Catalog No. ABIN7278754

Product Details anti-GAD65 Antibody

Target: GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))

Binding Specificity: AA 4-22

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GAD65 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Radioimmunoassay (RIA)

Sequence: GSGFWSFGSE DGSGDSEN

Purification: Affinity purified

Immunogen: Synthetic peptide: GSGFWSFGSEDGSGDSEN conjugated to KLH, corresponding to amino acids 4-22 of Human GAD65

Clone: 144

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try WB: Use a concentration of 1 μg/mL. Predicted molecular weight: 65 kDa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody containing PBS 0.1 % sodium azide,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-GAD65 antibody (ABIN7278754)

Singh, Raina, Chavali, Dubash, Kadreppa, Parab, Chattopadhyay: "Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment." in: BMC molecular biology, Vol. 13, pp. 28, (2012) (PubMed).

Steed, Gilliam, Harris, Lernmark, Hampe: "Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein." in: Journal of immunological methods, Vol. 334, Issue 1-2, pp. 114-21, (2008) (PubMed).

Hampe, Lundgren, Daniels, Hammerle, Marcovina, Lernmark: "A novel monoclonal antibody specific for the N-terminal end of GAD65." in: Journal of neuroimmunology, Vol. 113, Issue 1, pp. 63-71, (2001) (PubMed).

Target Details for GAD65

Target: GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))

Alternative Name: GAD65 (GAD2 Products)

Synonyms: GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody

Background: Synonyms:
65 kDa glutamic acid decarboxylase antibody,DCE 2 antibody,DCE2 antibody,GAD 2 antibody,GAD 65antibody,GAD-2 antibody,GAD-65 antibody,GAD2 antibody,Glutamate Decarboxylase 2 (pancreatic islets and brain65kDa) antibody,Glutamate Decarboxylase 2 antibody,Glutamate Decarboxylase 65 antibody,Glutamate decarboxylase65 kDa isoform antibody,Glutamic Acid Decarboxylase 2 antibody,Glutamic Acid Decarboxylase 65antibody

Gene ID: 2572, 14417, 24380

OMIM: 138275

UniProt: Q548L4