CYBA antibody

Catalog No. ABIN1042638

Product Details anti-CYBA Antibody

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYBA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificity: P22phox 165-KKPSE-169

Purification: Protein G purified

Immunogen: Partially purified human neutrophil flavocytochrome b (heparin Ultrogellectin affinity purification in octyl glucoside)

Clone: CS9

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try, WB: Use at 1:1000. Predicted molecular weight: 21 kDa ICC/IF: 1:100

Comment:

Myeloma, fusion partners: P3U1 myeloma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Affinity purified antiserum containing PBS 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-CYBA antibody (ABIN1042638)

Taniguchi, Ohno: "ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 601-8, (2008) (PubMed).

Taylor, Burritt, Baniulis, Foubert, Lord, Dinauer, Parkos, Jesaitis: "Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 12, pp. 7349-57, (2004) (PubMed).

Target Details for CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Alternative Name: Cytochrome b245 Light Chain  (CYBA Products)

Synonyms: zgc:66077 antibody, MGC80750 antibody, CYBA antibody, p22-phox antibody, p22phox antibody, p22-PHOX antibody, b558 antibody, nmf333 antibody, P22-PHOX antibody, cytochrome b-245, alpha polypeptide antibody, cytochrome b-245 alpha polypeptide L homeolog antibody, cytochrome b-245 alpha polypeptide antibody, cytochrome b-245 light chain-like antibody, cytochrome b-245 alpha chain antibody, p22-phox antibody, cyba antibody, cyba.L antibody, CYBA antibody, LOC101328418 antibody, Cyba antibody

Background: Synonyms:
Superoxide-generating NADPH oxidase light chain subunit antibody,CYBA antibody,Cytochrome b(558) alphachain antibody,Cytochrome b558 subunit alpha antibody,Neutrophil cytochrome b 22 kDa polypeptide antibody,p22phagocyte B-cytochrome antibody,p22-phox antibody,p22phox antibody

Gene ID: 1535, 21577

OMIM: 608508

UniProt: Q01062

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis