Sad1 and UNC84 Domain Containing 2 (SUN2) antibody

Antigen: Sad1 and UNC84 Domain Containing 2 (SUN2)

Synonyms: UNC84B, KIAA0668, MGC133055, MGC133056

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Catalog no.: ABIN1042681

Additional Information

Alternative name: SUN2

Immunogen: GST-Sun2 peptide

Format: Liquid

Description: Synonyms: FRIGG antibody,Rab5 interacting protein antibody,RAB5IP antibody,Sad1 unc84 domain protein antibody,Sad1/unc84 protein-like antibody,UNC 84B antibody,unc84 homolog B (C. elegans) antibody,unc84 homolog B antibody,UNC84B antibody

Specificity: Human SUN2

Comments:

SUN proteins form part of the LINC complex - a protein bridge that spans the nuclear envelope linking the nucleoskeleten to the actin cytoskeleten. They are located on the inner nuclear membrane side of the complex. The LINC complex is thought to function in controlling nuclear position, contributing to mechanical resistance and the overall architecture of the cell. SUN2 can exist in a heterodimer with SUN1. Both can interact with lamins and nesprins in the nuclear envelope

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a

Purification: Serum

Research Area: Signaling, Cytoskeleton, Microfilaments

Restrictions: For Research Use only

Images

anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibody

Publications

Product: Hodzic, Yeater, Bengtsson et al.: "Sun2 is a novel mammalian inner nuclear membrane protein." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25805-12, 2004 (PubMed).