Sad1 and UNC84 Domain Containing 2 (SUN2) antibody

Details for Product No. ABIN1042681
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Antigen
Synonyms UNC84B, B230369L08Rik, C030011B15, Unc84b, RGD1563141
Reactivity
Human
(15), (4), (4), (2), (2)
Host
Rabbit
(16)
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
(16), (7), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mL
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Catalog No. ABIN1042681
576.05 $
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Immunogen GST-Sun2 peptide
Alternative Name SUN2
Background Synonyms:
FRIGG antibody,Rab5 interacting protein antibody,RAB5IP antibody,Sad1 unc84 domain protein antibody,Sad1/unc84 protein-like antibody,UNC 84B antibody,unc84 homolog B (C. elegans) antibody,unc84 homolog B antibody,UNC84B antibody
Research Area Signaling, Cytoskeleton, Microfilaments
Application Notes Optimal antibody dilution should be determined by titration
Comment

SUN proteins form part of the LINC complex - a protein bridge that spans the nuclear envelope linking the nucleoskeleten to the actin cytoskeleten. They are located on the inner nuclear membrane side of the complex. The LINC complex is thought to function in controlling nuclear position, contributing to mechanical resistance and the overall architecture of the cell. SUN2 can exist in a heterodimer with SUN1. Both can interact with lamins and nesprins in the nuclear envelope

Restrictions For Research Use only
Format Liquid
Buffer Serum containing 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibody anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibody
Product cited in: Hodzic, Yeater, Bengtsson et al.: "Sun2 is a novel mammalian inner nuclear membrane protein." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25805-12, 2004 (PubMed).

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