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Estrogen Receptor (ER) antibody
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|5 references available|
|Quantity||5ml (1 to 4 ug/ml)|
|Price||464.20 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 3 to 4 Business Days|
|Alternative name||Oestrogen Receptor|
|Immunogen||Prokaryotic recombinant protein corresponding to the full-length estrogen receptor molecule.|
|Specificity||This antibody is specific to the estrogen receptor and recognizes full-length polypeptide chain of the receptor. The nuclei of the estrogen receptor positive cells stain very strongly with this antibody, without any staining in the cytoplasm.|
|Synonyms||LOC398733, LOC398734, ERa, ESR, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ESR1, NR3A1, eralpha, zfER[a], Errra, ERRalpha, ESRRA, err1, erra, esrral, erralpha, LOC100125507, ESTRRA, esrl1, nr3b1, MGC147343, ERRa, ER[b]1, zfER[b]1, MGC103724, zfER-beta1, erb2, erb1, CERB, ESR2, ERB, erb, esrb, estrb, nr3a2, ERbeta, er-beta, esr-beta, ERBETA, er, ER-beta, ER[b], Estrb, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, LOC100125508, errb2, ER, Era, ESRA, DKFZp686N23123, 7B4, CD144, FLJ17376, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, Esr, RNESTROR, ERALPHA, esr, esr1, nr3a1, AAC2, PNAT, XER, era, esra, xesr-1, xlERalpha1, xlERalpha2|
|Application Notes||Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma. Cellular localization: Nuclear|
|Concentration||1 to 4 ug/ml|
|Buffer||This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.|
|Storage||Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.|
|Research Area||Hormones, Receptors|
|Restrictions||For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union|
Bur, Zimarowski, Schnitt et al.: "Estrogen receptor immunohistochemistry in carcinoma in situ of the breast." in: Cancer, Vol. 69, Issue 5, pp. 1174-81, 1992 (PubMed).
Graham, Jin, Lloyd: "Detection of estrogen receptor in paraffin-embedded sections of breast carcinoma by immunohistochemistry and in situ hybridization." in: The American journal of surgical pathology, Vol. 15, Issue 5, pp. 475-85, 1991 (PubMed).
Pertschuk, Kim, Nayer et al.: "Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival." in: Cancer, Vol. 66, Issue 8, pp. 1663-70, 1990 (PubMed).
Kumar, Green, Stack et al.: "Functional domains of the human estrogen receptor." in: Cell, Vol. 51, Issue 6, pp. 941-51, 1988 (PubMed).
Ozono, Sato, Ito et al.: "Immunohistochemical evidence that tumors elicit the synthesis of estrogen receptors in the submandibular gland of female rats." in: Experientia, Vol. 51, Issue 3, pp. 220-2, 1995 (PubMed).