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Details for Product No. ABIN105287

Nuclear Factor-KB P65 (NFkBP65) (pSer529) antibody

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Antigen
Synonyms C-Rel, Xrel2, c-rel, rel-A, v-rel, xrel, zgc:100833, p65, NFkB
Epitope
»Alternatives pSer529
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
Pubmed 3 references available
Catalog no. ABIN105287
Quantity 100 µL
Price
361.90 $   Plus shipping costs $45.00 and if applicable $26.40 dry ice
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Availability Will be delivered in 2 to 3 Business Days
Immunogen NFkB p65 (Rel A) peptide corresponding to a region near phospho Serine 529 of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Characteristics Concentration Definition: by Refractometry
Purification Antiserum
Alternative Name NFkB p65 (RelA)
Background NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Anti-NFkB antibody is ideal for Cell Biology, Nuclear Signaling, Neuroscience and Signal Transduction Research
Synonyms: NFKB, nfkb, NF-kB, NF-kappaB, NFkappaB
Gene ID 5970
NCBI Accession 223468676
UniProt Q04206
Application Notes Anti-phospho NFkB antibody reacts human pS529 p65 and shows minimal reactivity by western blot with non-phosphorylated p65 and minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.  Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.
Restrictions For Research Use only
Format Liquid
Concentration 75 mg/mL
Preservative Sodium azide
Storage -20 °C
Shakibaei, John, Schulze-Tanzil et al.: "Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis." in: Biochemical pharmacology, Vol. 73, Issue 9, pp. 1434-45, 2007 (PubMed).

Amith, Jayanth, Franchuk et al.: "Neu1 desialylation of sialyl alpha-2,3-linked beta-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling." in: Cellular signalling, 2009 (PubMed).

Gavert, Ben-Shmuel, Lemmon et al.: "Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells." in: Journal of cell science, Vol. 123, Issue Pt 12, pp. 2135-43, 2010 (PubMed).

Alternatives for antigen "Nuclear Factor-KB P65 (NFkBP65)", type "Antibodies"
Hosts (691), (54), (6), (4), (1)
Reactivities (734), (426), (348), (81), (78), (78), (38), (8), (6), (3), (2), (2), (2), (2), (2), (1)
Applications (553), (266), (247), (189), (110), (104), (100), (31), (17), (14), (13), (7), (5), (4), (3), (2), (2), (1)
Conjugates (16), (11), (10), (10), (10), (10), (10), (10), (10), (10), (10), (2), (1), (1)
Epitopes (47), (43), (42), (42), (31), (31), (29), (28), (27), (22), (18), (15), (12), (7), (6), (6), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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