SPATA6 antibody (C-Term)

Catalog No. ABIN1077368

Product Details anti-SPATA6 Antibody

Target: SPATA6 (Spermatogenesis Associated 6 (SPATA6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity: At least three isoforms of SPATA6 are known to exist, this antibody will detect only the longest two isoforms. SPATA6 antibody is predicted to not cross-react with other SPATA protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: SPATA6 antibody was raised against a AA 14 synthetic peptide near the carboxy terminus of human SPATA6.

Isotype: IgG

Application Details

Application Notes: SPATA6 antibody can be used for detection of SPATA6 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: SPATA6 antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.

Expiry Date: 12 months

Target Details for SPATA6

Target: SPATA6 (Spermatogenesis Associated 6 (SPATA6))

Alternative Name: SPATA6 (SPATA6 Products)

Synonyms: HASH antibody, SRF-1 antibody, SRF1 antibody, 1700062C23Rik antibody, AI790763 antibody, Hash antibody, KRP antibody, Mash antibody, spermatogenesis associated 6 antibody, SPATA6 antibody, Spata6 antibody

Background: Synonyms:
Spermatogenesis associated protein 6, HASH, SRF1, SRF-1

The development of spermatogonial stem cells into spermatozoa, i.e., spermatogenesis, is a highly ordered process that requires multiple proteins, including some that are testis-specific or testis-specific isoforms of genes that are expressed in other tissues. One such protein is SPATA6: while its full-length isoform is expressed in multiple tissues including thymus, brain and testis, the shorter isoform is expressed only in testis. It has some homology to the motor domain of kinesin related proteins and with the C. elegans neural calcium sensor protein NCS-2.

Gene ID: 54558

NCBI Accession: NP_061946