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Myc Target 1 antibody (C-Term)

MYCT1 Reactivity: Human, Mouse, Rat WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1077374
  • Target See all Myc Target 1 (MYCT1) Antibodies
    Myc Target 1 (MYCT1)
    Binding Specificity
    • 15
    • 10
    • 8
    • 7
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 37
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Myc Target 1 antibody is un-conjugated
    Application
    • 36
    • 17
    • 14
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Specificity
    At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
    Isotype
    IgG
    Top Product
    Discover our top product MYCT1 Primary Antibody
  • Application Notes
    MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
    Comment

    (CT) Myc target protein 1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Storage
    4 °C
    Storage Comment
    MYCT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    Expiry Date
    12 months
  • Target
    Myc Target 1 (MYCT1)
    Alternative Name
    MYCT1 (MYCT1 Products)
    Synonyms
    MYCT1 antibody, MGC147166 antibody, si:dkey-12h9.2 antibody, MTLC antibody, 1110020B04Rik antibody, AI225941 antibody, AI642973 antibody, Mtmc1 antibody, myc target 1 antibody, MYC target 1 antibody, myc target 1a antibody, MYCT1 antibody, myct1 antibody, myct1a antibody, Myct1 antibody
    Background
    MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
    Synonyms: Myc target protein 1, myc target in myeloid cells 1, MTLC, MT-MC1
    Molecular Weight
    26 kDa
    Gene ID
    80177
    NCBI Accession
    NP_079383
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