WIPI1 antibody (C-Term)

Catalog No. ABIN1077376

Product Details anti-WIPI1 Antibody

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: At least two isoforms of WIPI1 are known to exist, this antibody will detect both isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogen: WIPI1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WIPI1.

Isotype: IgG

Application Details

Application Notes: WIPI1 antibody can be used for detection of Wipi1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Comment:

(CT) WD repeat domain phosphoinositide interacting 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: WIPI1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for WIPI1

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Alternative Name: WIPI1 (WIPI1 Products)

Synonyms: ATG18 antibody, ATG18A antibody, WIPI49 antibody, 4930533H01Rik antibody, AW411817 antibody, D11Ertd498e antibody, RGD1307754 antibody, zgc:64205 antibody, WIPI1 antibody, atg18 antibody, wipi49 antibody, MGC145296 antibody, rgs9 antibody, wipi1 antibody, zgc:152760 antibody, WD repeat domain, phosphoinositide interacting 1 antibody, WD repeat domain, phosphoinositide interacting 1 S homeolog antibody, regulator of G protein signaling 9a antibody, WIPI1 antibody, Wipi1 antibody, wipi1 antibody, wipi1.S antibody, rgs9a antibody

Background: WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.
Synonyms: WD repeat domain phosphoinositide interacting 1, ATG18, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WIPI-1, WIPI49

Molecular Weight: 49 kDa

Gene ID: 55062

NCBI Accession: NP_060453

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling