PANX1 antibody (N-Term)

Catalog No. ABIN1077400

Product Details anti-PANX1 Antibody

Target: PANX1 (Pannexin 1 (PANX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PANX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Two transcript variants encoding different isoforms have been found for this gene.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.

Isotype: IgG

Application Details

Application Notes: PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Comment:

(NT) Pannexin 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: PANX1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for PANX1

Target: PANX1 (Pannexin 1 (PANX1))

Alternative Name: PANX1 (PANX1 Products)

Synonyms: panx1 antibody, zgc:55631 antibody, PANX1 antibody, px1 antibody, mrs1 antibody, pannexin1 antibody, Pannexin-1 antibody, MRS1 antibody, PX1 antibody, UNQ2529 antibody, AI847747 antibody, pannexin 1a antibody, pannexin 1 antibody, Pannexin 1 antibody, panx1a antibody, PANX1 antibody, panx1 antibody, Panx1 antibody

Background: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Synonyms: Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028

Molecular Weight: 47 kDa

Gene ID: 24145

NCBI Accession: NP_056183