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FOXP3 antibody (C-Term)

FOXP3 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN1077427
  • Target See all FOXP3 Antibodies
    FOXP3 (Forkhead Box P3 (FOXP3))
    Binding Specificity
    • 22
    • 16
    • 15
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 154
    • 112
    • 45
    • 25
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 115
    • 58
    • 11
    • 2
    Rabbit
    Clonality
    • 116
    • 70
    Monoclonal
    Conjugate
    • 88
    • 18
    • 12
    • 12
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FOXP3 antibody is un-conjugated
    Application
    • 132
    • 83
    • 69
    • 38
    • 37
    • 27
    • 27
    • 19
    • 18
    • 17
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
    Isotype
    IgG
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • Application Notes
    FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.
    Comment

    (CT) Forkhead box P3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Storage
    4 °C
    Storage Comment
    FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    Expiry Date
    12 months
  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Alternative Name
    FOXP3 (FOXP3 Products)
    Synonyms
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    Background
    FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
    Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin
    Molecular Weight
    47 kDa (calculated)
    Gene ID
    50943
    NCBI Accession
    NP_054728
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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