TPT1 antibody

Catalog No. ABIN1077430

Product Details anti-TPT1 Antibody

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.

Isotype: IgG

Application Details

Application Notes: TPT1 antibody can be used for detection of TPT1 by Western blot at 0.5 - 1 μg/mL.

Comment:

(IN) Translationally-controlled tumor protein 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: TPT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TPT1 (TPT1 Products)

Synonyms: HRF antibody, TCTP antibody, p02 antibody, Trt antibody, p21 antibody, p23 antibody, TPT1 antibody, TCT1 antibody, tctp antibody, fa28a02 antibody, id:ibd2078 antibody, wu:fa28a02 antibody, PCHK23 antibody, hrf antibody, MGC79720 antibody, Tpt1 antibody, translationally controlled tumor protein antibody, CG4800 antibody, Dmel\\CG4800 antibody, dTCTP antibody, Tctp antibody, tumor protein, translationally-controlled 1 antibody, tumor protein, translationally-controlled 1 L homeolog antibody, translationally-controlled tumor protein antibody, translationally controlled tumor protein antibody, translationally controlled tumor-like protein antibody, Translationally controlled tumor protein antibody, translationally-controlled tumor protein homolog antibody, P23 tumor protein-like antibody, TPT1 antibody, Tpt1 antibody, tpt1 antibody, tpt1.L antibody, LOC711798 antibody, TCTP antibody, LOC548038 antibody, Tctp antibody, LOC108708523 antibody, LOC109404863 antibody, LOC105389397 antibody, LOC102577554 antibody

Background: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Synonyms: Tumor protein translationally-controlled 1, translationally-controlled tumor protein, TCTP, fortilin, histamine-releasing factor, HRF, p23

Molecular Weight: 19 kDa (calculated)

Gene ID: 7178

NCBI Accession: NP_003286

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling