TSC22D3 antibody (N-Term)
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- Target See all TSC22D3 Antibodies
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TSC22D3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3.
- Isotype
- IgG
- Top Product
- Discover our top product TSC22D3 Primary Antibody
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- Application Notes
- TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μg/mL.
- Comment
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(NT) TSC22 domain family member 3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C
- Storage Comment
- TSC22D3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- Alternative Name
- TSC22D3 (TSC22D3 Products)
- Synonyms
- dsipi antibody, MGC53285 antibody, zgc:65831 antibody, zgc:77028 antibody, TSC22D3 antibody, GILZ antibody, gilz antibody, tsc-22r antibody, DIP antibody, DSIPI antibody, TSC-22R antibody, hDIP antibody, Dsip1 antibody, Gilz antibody, Tilz3 antibody, Dsipi antibody, DSIP antibody, TSC22 domain family member 3 L homeolog antibody, TSC22 domain family, member 3 antibody, TSC22 domain family member 3 antibody, tsc22d3.L antibody, tsc22d3 antibody, TSC22D3 antibody, Tsc22d3 antibody
- Background
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The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-kB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
Synonyms: TSC22 domain family member 3, TSC-22 related protein, delta sleep inducing peptide, DIP, DSIPI, GILZ, TSC-22R, DSIP-immunoreactive leucine zipper protein - Molecular Weight
- 22 kDa (calculated)
- Gene ID
- 1831
- NCBI Accession
- NP_932174
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