GRIP1 antibody (C-Term)

Catalog No. ABIN1077440

Product Details anti-GRIP1 Antibody

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1.

Isotype: IgG

Application Details

Application Notes: GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μg/mL.

Comment:

(CT) Glutamate receptor interacting protein 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: GRIP1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for GRIP1

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Alternative Name: GRIP1 (GRIP1 Products)

Synonyms: GRIP antibody, 4931400F03Rik antibody, eb antibody, grip antibody, xgrip1 antibody, GRIP1 antibody, si:dkey-244b23.1 antibody, si:dkey-6a5.1 antibody, glutamate receptor interacting protein 1 antibody, glutamate receptor interacting protein 1 S homeolog antibody, glutamate receptor-interacting protein 1 antibody, GRIP1 antibody, Grip1 antibody, grip1.S antibody, LOC525592 antibody, grip1 antibody

Background: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
Synonyms: Glutamate receptor interacting protein 1, GRIP-1

Molecular Weight: 118 kDa (calculated)

Gene ID: 23426

NCBI Accession: NP_066973

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway