Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PTRF antibody (C-Term)

PTRF Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1077453
  • Target See all PTRF Antibodies
    PTRF (Polymerase I and Transcript Release Factor (PTRF))
    Binding Specificity
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 15
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 32
    • 5
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTRF antibody is un-conjugated
    Application
    • 23
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF.
    Isotype
    IgG
    Top Product
    Discover our top product PTRF Primary Antibody
  • Application Notes
    PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μg/mL.
    Comment

    (CT) Polymerase I and transcript release factor

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Storage
    4 °C/-20 °C
  • Target
    PTRF (Polymerase I and Transcript Release Factor (PTRF))
    Alternative Name
    PTRF (PTRF Products)
    Synonyms
    MGC53017 antibody, MGC89141 antibody, PTRF antibody, fd20g07 antibody, ptrf antibody, wu:fd20g07 antibody, zgc:162917 antibody, CAVIN antibody, CAVIN1 antibody, CGL4 antibody, cavin-1 antibody, 2310075E07Rik antibody, AW546441 antibody, Cav-p60 antibody, Cavin antibody, caveolae associated protein 1 L homeolog antibody, polymerase I and transcript release factor antibody, caveolae associated protein 1 antibody, caveolae associated protein 1b antibody, caveolae associated 1 antibody, cavin1.L antibody, PTRF antibody, cavin1 antibody, CAVIN1 antibody, cavin1b antibody, Cavin1 antibody
    Background
    The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
    Synonyms: Polymerase I and transcript release factor, FKSG13, CAVIN, CAVIN1, CGL4, cavin-1, TTF-I interacting peptide 12
    Molecular Weight
    43 kDa
    Gene ID
    284119
    NCBI Accession
    NP_036364
You are here:
Support