HAVCR1 antibody (AA 22-237)

Catalog No. ABIN1077715

Product Details anti-HAVCR1 Antibody

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Binding Specificity: AA 22-237

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAVCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

Specificity: The antibody is a rabbit polyclonal antibody raised against Kim1. It has been selected for its ability to recognize Kim1 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Kidney Injury Molecule 1 (Kim1) corresdonding to Tyr22~Gly237 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

References for anti-HAVCR1 antibody (ABIN1077715)

Schindler, Bondeva, Schindler, Claus, Franke, Wolf: "Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 31, Issue 7, pp. 1100-13, (2016) (PubMed).

Target Details for HAVCR1

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Alternative Name: Kidney Injury Molecule 1 (HAVCR1 Products)

Synonyms: HAVCR antibody, HAVCR-1 antibody, KIM-1 antibody, KIM1 antibody, TIM antibody, TIM-1 antibody, TIM1 antibody, TIMD-1 antibody, TIMD1 antibody, Kim1 antibody, HAVCR1 antibody, LOC100226241 antibody, AI503787 antibody, Tim1 antibody, Timd1 antibody, hepatitis A virus cellular receptor 1 antibody, hepatitis A virus cellular receptor 1 homolog antibody, HAVCR1 antibody, Havcr1 antibody, LOC100226241 antibody

Target Type: Virus

Background: HAVCR1, TIM1, TIMD1, HAVCR, Hepatitis A Virus Cellular Receptor 1, T Cell Immunoglobulin And Mucin Domain-Containing Protein 1, T-cell immunoglobulin mucin receptor 1

Molecular Weight: 25.15 kDa