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Tenascin C (TNC) antibody

Details for Product No. ABIN108414, Supplier: Log in to see
Antigen
  • 150-225
  • AI528729
  • C130033P17Rik
  • cytotactin
  • GMEM
  • GP
  • HXB
  • Hxb
  • JI
  • P230
  • Ten
  • tenascin-C
  • tenc
  • TN
  • tn
  • TN-C
  • wu:fk04d02
Reactivity
Human
266
71
62
5
2
2
1
1
1
1
1
Host
Mouse
147
116
14
4
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
21
19
15
5
5
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
156
120
98
73
52
42
40
36
23
22
8
5
1
1
1
1
Supplier
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Immunogen Monoclonal antibody (Mab) to tenascin-C is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Purified tenascin-C from human fetal fibroblasts was used as an immunogen.
Clone EB2
Isotype IgG1
Specificity The antibody reacts with the 4th and 5th fibronectin-like repeats of human tenascin-C polypeptides of Mr 250000 and 180000. The antibody crossreacts with human, guinea pig and rabbit
Alternative Name Tenascin C (TNC Antibody Abstract)
Background Monoclonal Antibody to Human Extracellular Matrix Components
Research Area Extracellular Matrix
Application Notes No reactivity with paraffin sections. Working dilution in westem blotting is at least 1:1000.
Restrictions For Research Use only
Storage 4 °C
Supplier Images
 image for anti-Tenascin C (TNC) antibody (ABIN108414) Carcinoma in situ, vulva (MAb EB2, tenascin)
Immunohistochemistry (IHC) image for anti-Tenascin C (TNC) antibody (ABIN108414) anti-Tenascin C (TNC) antibody (Image 2)
Background publications Li TF,Warris V,Ma J,Lassus J,Yoshida T,Santavirta S,Virtanen I,Konttinen YT: "Distribution of tenascin-X in different synovial samples and synovial membrane-like interface tissue from aseptic loosening of total hip replacement." in: Rheumatol Int, Vol. 19, Issue 5, pp. 177-83, 2007 (PubMed).

Korhonen, Ormio, Burgeson, Virtanen, Savilahti: "Unaltered distribution of laminins, fibronectin, and tenascin in celiac intestinal mucosa." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 48, Issue 7, pp. 1011-20, 2000 (PubMed).

Karjalainen, Laitinen, Sue-Chu, Altraja, Bjermer, Laitinen: "Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine." in: American journal of respiratory and critical care medicine, Vol. 161, Issue 6, pp. 2086-91, 2000 (PubMed).

Järvinen, Jozsa, Kannus, Järvinen, Kvist, Hurme, Isola, Kalimo, Järvinen: "Mechanical loading regulates tenascin-C expression in the osteotendinous junction." in: Journal of cell science, Vol. 112 Pt 18, pp. 3157-66, 2000 (PubMed).

Feng, Yang, Huang, Kennedy, Turi, Thompson, Libby, Lee: "Transcriptional profile of mechanically induced genes in human vascular smooth muscle cells." in: Circulation research, Vol. 85, Issue 12, pp. 1118-23, 2000 (PubMed).

Yamamoto, Dang, Kennedy, Osathanondh, Kelly, Lee: "Induction of tenascin-C in cardiac myocytes by mechanical deformation. Role of reactive oxygen species." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21840-6, 1999 (PubMed).

Ribatti D,Loverro G,Vacca A,Greco P,Roncali L,Selvaggi L: "Expression of tenascin is related to angiogenesis in pre-eclampsia." in: Eur J Clin Invest, Vol. 28, Issue 5, pp. 373-8, 1998 (PubMed).

Kaarteenaho-Wiik R,Mertaniemi P,Sajanti E,Soini Y,Paakko P: "Tenascin is increased in epithelial lining fluid in fibrotic lung disorders." in: Lung, Vol. 176, Issue 6, pp. 371-80, 1998 (PubMed).

Tuori, Virtanen, Aine, Uusitalo: "The expression of tenascin and fibronectin in keratoconus, scarred and normal human cornea." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 235, Issue 4, pp. 222-9, 1997 (PubMed).

Laitinen A,Altraja A,Kampe M,Linden M,Virtanen I,Laitinen LA: "Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid." in: Am J Respir Crit Care Med, Vol. 156, Issue 3 Pt 1, pp. 951-8, 1997 (PubMed).

Kaarteenaho-Wiik R,Tani T,Sormunen R,Soini Y,Virtanen I,Paakko P: "Tenascin immunoreactivity as a prognostic marker in usual interstitial pneumonia." in: Am J Respir Crit Care Med, Vol. 154, Issue 2 Pt 1, pp. 511-8, 1996 (PubMed).

Lohi J,Leivo I,Tani T,Kiviluoto T,Kivilaakso E,Burgeson RE,Virtanen I: "Laminins, tenascin and type VII collagen in colorectal mucosa." in: Histochem J, Vol. 28, Issue 6, pp. 431-40, 1996 (PubMed).

Vesaluoma, Ylätupa, Mertaniemi, Tervo, Partanen, Tervo: "Increased release of tenascin in tear fluid after photorefractive keratectomy." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 233, Issue 8, pp. 479-83, 1996 (PubMed).

Linnala, Kinnula, Laitinen, Lehto, Virtanen: "Transforming growth factor-beta regulates the expression of fibronectin and tenascin in BEAS 2B human bronchial epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 13, Issue 5, pp. 578-85, 1995 (PubMed).

Koukoulis, Gould, Bhattacharyya, Gould, Howeedy, Virtanen: "Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: biologic and pathologic implications." in: Human pathology, Vol. 22, Issue 7, pp. 636-43, 1991 (PubMed).

Howeedy, Virtanen, Laitinen, Gould, Koukoulis, Gould: "Differential distribution of tenascin in the normal, hyperplastic, and neoplastic breast." in: Laboratory investigation, a journal of technical methods and pathology, Vol. 63, Issue 6, pp. 798-806, 1991 (PubMed).