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Tenascin C (TNC) antibody

Details for Product No. ABIN108414, Supplier: Log in to see
Antigen
  • tn
  • 150-225
  • GMEM
  • GP
  • HXB
  • JI
  • TN
  • TN-C
  • AI528729
  • C130033P17Rik
  • Hxb
  • Ten
  • cytotactin
  • tenascin-C
  • P230
  • tenc
  • wu:fk04d02
  • tenascin C
  • tnc
  • TNC
  • MCYG_00667
  • Tnc
Reactivity
Human
269
82
72
6
3
2
2
1
1
1
Host
Mouse
145
121
14
4
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
21
19
15
5
5
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
158
117
107
63
60
40
39
38
29
26
7
6
5
5
1
1
1
Options
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Immunogen Monoclonal antibody (Mab) to tenascin-C is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Purified tenascin-C from human fetal fibroblasts was used as an immunogen.
Clone EB2
Isotype IgG1
Specificity The antibody reacts with the 4th and 5th fibronectin-like repeats of human tenascin-C polypeptides of Mr 250000 and 180000. The antibody crossreacts with human, guinea pig and rabbit
Alternative Name Tenascin C (TNC Antibody Abstract)
Background Monoclonal Antibody to Human Extracellular Matrix Components
Research Area Extracellular Matrix
Pathways Regulation of Muscle Cell Differentiation
Application Notes No reactivity with paraffin sections. Working dilution in westem blotting is at least 1:1000.
Restrictions For Research Use only
Storage 4 °C
Supplier Images
 image for anti-Tenascin C (TNC) antibody (ABIN108414) Carcinoma in situ, vulva (MAb EB2, tenascin)
Immunohistochemistry (IHC) image for anti-Tenascin C (TNC) antibody (ABIN108414) anti-Tenascin C (TNC) antibody (Image 2)
Background publications Li TF,Warris V,Ma J,Lassus J,Yoshida T,Santavirta S,Virtanen I,Konttinen YT: "Distribution of tenascin-X in different synovial samples and synovial membrane-like interface tissue from aseptic loosening of total hip replacement." in: Rheumatol Int, Vol. 19, Issue 5, pp. 177-83, 2007 (PubMed).

Korhonen, Ormio, Burgeson, Virtanen, Savilahti: "Unaltered distribution of laminins, fibronectin, and tenascin in celiac intestinal mucosa." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 48, Issue 7, pp. 1011-20, 2000 (PubMed).

Karjalainen, Laitinen, Sue-Chu, Altraja, Bjermer, Laitinen: "Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine." in: American journal of respiratory and critical care medicine, Vol. 161, Issue 6, pp. 2086-91, 2000 (PubMed).

Järvinen, Jozsa, Kannus, Järvinen, Kvist, Hurme, Isola, Kalimo, Järvinen: "Mechanical loading regulates tenascin-C expression in the osteotendinous junction." in: Journal of cell science, Vol. 112 Pt 18, pp. 3157-66, 2000 (PubMed).

Feng, Yang, Huang, Kennedy, Turi, Thompson, Libby, Lee: "Transcriptional profile of mechanically induced genes in human vascular smooth muscle cells." in: Circulation research, Vol. 85, Issue 12, pp. 1118-23, 2000 (PubMed).

Yamamoto, Dang, Kennedy, Osathanondh, Kelly, Lee: "Induction of tenascin-C in cardiac myocytes by mechanical deformation. Role of reactive oxygen species." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21840-6, 1999 (PubMed).

Ribatti D,Loverro G,Vacca A,Greco P,Roncali L,Selvaggi L: "Expression of tenascin is related to angiogenesis in pre-eclampsia." in: Eur J Clin Invest, Vol. 28, Issue 5, pp. 373-8, 1998 (PubMed).

Kaarteenaho-Wiik R,Mertaniemi P,Sajanti E,Soini Y,Paakko P: "Tenascin is increased in epithelial lining fluid in fibrotic lung disorders." in: Lung, Vol. 176, Issue 6, pp. 371-80, 1998 (PubMed).

Tuori, Virtanen, Aine, Uusitalo: "The expression of tenascin and fibronectin in keratoconus, scarred and normal human cornea." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 235, Issue 4, pp. 222-9, 1997 (PubMed).

Laitinen A,Altraja A,Kampe M,Linden M,Virtanen I,Laitinen LA: "Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid." in: Am J Respir Crit Care Med, Vol. 156, Issue 3 Pt 1, pp. 951-8, 1997 (PubMed).

Kaarteenaho-Wiik R,Tani T,Sormunen R,Soini Y,Virtanen I,Paakko P: "Tenascin immunoreactivity as a prognostic marker in usual interstitial pneumonia." in: Am J Respir Crit Care Med, Vol. 154, Issue 2 Pt 1, pp. 511-8, 1996 (PubMed).

Lohi J,Leivo I,Tani T,Kiviluoto T,Kivilaakso E,Burgeson RE,Virtanen I: "Laminins, tenascin and type VII collagen in colorectal mucosa." in: Histochem J, Vol. 28, Issue 6, pp. 431-40, 1996 (PubMed).

Vesaluoma, Ylätupa, Mertaniemi, Tervo, Partanen, Tervo: "Increased release of tenascin in tear fluid after photorefractive keratectomy." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 233, Issue 8, pp. 479-83, 1996 (PubMed).

Linnala, Kinnula, Laitinen, Lehto, Virtanen: "Transforming growth factor-beta regulates the expression of fibronectin and tenascin in BEAS 2B human bronchial epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 13, Issue 5, pp. 578-85, 1995 (PubMed).

Koukoulis, Gould, Bhattacharyya, Gould, Howeedy, Virtanen: "Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: biologic and pathologic implications." in: Human pathology, Vol. 22, Issue 7, pp. 636-43, 1991 (PubMed).

Howeedy, Virtanen, Laitinen, Gould, Koukoulis, Gould: "Differential distribution of tenascin in the normal, hyperplastic, and neoplastic breast." in: Laboratory investigation, a journal of technical methods and pathology, Vol. 63, Issue 6, pp. 798-806, 1991 (PubMed).