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Tenascin C (TNC) antibody

Details for Product No. ABIN108414, Supplier: Log in to see
Antigen
  • tn
  • 150-225
  • GMEM
  • GP
  • HXB
  • JI
  • TN
  • TN-C
  • AI528729
  • C130033P17Rik
  • Hxb
  • Ten
  • cytotactin
  • tenascin-C
  • P230
  • tenc
  • wu:fk04d02
Reactivity
Human
192
51
43
5
2
2
1
1
1
1
1
Host
Mouse
115
76
13
4
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
18
16
12
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
130
85
50
48
24
23
22
18
11
8
5
4
1
1
1
1
Supplier
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Immunogen Monoclonal antibody (Mab) to tenascin-C is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Purified tenascin-C from human fetal fibroblasts was used as an immunogen.
Clone EB2
Isotype IgG1
Specificity The antibody reacts with the 4th and 5th fibronectin-like repeats of human tenascin-C polypeptides of Mr 250000 and 180000. The antibody crossreacts with human, guinea pig and rabbit
Alternative Name Tenascin C (TNC Antibody Abstract)
Background Monoclonal Antibody to Human Extracellular Matrix Components
Research Area Extracellular Matrix
Application Notes No reactivity with paraffin sections. Working dilution in westem blotting is at least 1:1000.
Restrictions For Research Use only
Storage 4 °C
Supplier Images
 image for anti-Tenascin C (TNC) antibody (ABIN108414) Carcinoma in situ, vulva (MAb EB2, tenascin)
Immunohistochemistry (IHC) image for anti-Tenascin C (TNC) antibody (ABIN108414) anti-Tenascin C (TNC) antibody (Image 2)
Background publications Li TF, Warris V, Ma J et al.: "Distribution of tenascin-X in different synovial samples and synovial membrane-like interface tissue from aseptic loosening of total hip replacement." in: Rheumatol Int, Vol. 19, Issue 5, pp. 177-83, 2007 (PubMed).

Korhonen, Ormio, Burgeson et al.: "Unaltered distribution of laminins, fibronectin, and tenascin in celiac intestinal mucosa." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 48, Issue 7, pp. 1011-20, 2000 (PubMed).

Karjalainen, Laitinen, Sue-Chu et al.: "Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine." in: American journal of respiratory and critical care medicine, Vol. 161, Issue 6, pp. 2086-91, 2000 (PubMed).

Feng, Yang, Huang et al.: "Transcriptional profile of mechanically induced genes in human vascular smooth muscle cells." in: Circulation research, Vol. 85, Issue 12, pp. 1118-23, 2000 (PubMed).

Järvinen, Jozsa, Kannus et al.: "Mechanical loading regulates tenascin-C expression in the osteotendinous junction." in: Journal of cell science, Vol. 112 Pt 18, pp. 3157-66, 2000 (PubMed).

Yamamoto, Dang, Kennedy et al.: "Induction of tenascin-C in cardiac myocytes by mechanical deformation. Role of reactive oxygen species." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21840-6, 1999 (PubMed).

Kaarteenaho-Wiik R, Mertaniemi P, Sajanti E et al.: "Tenascin is increased in epithelial lining fluid in fibrotic lung disorders." in: Lung, Vol. 176, Issue 6, pp. 371-80, 1998 (PubMed).

Ribatti D, Loverro G, Vacca A et al.: "Expression of tenascin is related to angiogenesis in pre-eclampsia." in: Eur J Clin Invest, Vol. 28, Issue 5, pp. 373-8, 1998 (PubMed).

Laitinen A, Altraja A, Kampe M et al.: "Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid." in: Am J Respir Crit Care Med, Vol. 156, Issue 3 Pt 1, pp. 951-8, 1997 (PubMed).

Tuori, Virtanen, Aine et al.: "The expression of tenascin and fibronectin in keratoconus, scarred and normal human cornea." in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Vol. 235, Issue 4, pp. 222-9, 1997 (PubMed).

Lohi J, Leivo I, Tani T et al.: "Laminins, tenascin and type VII collagen in colorectal mucosa." in: Histochem J, Vol. 28, Issue 6, pp. 431-40, 1996 (PubMed).

Kaarteenaho-Wiik R, Tani T, Sormunen R et al.: "Tenascin immunoreactivity as a prognostic marker in usual interstitial pneumonia." in: Am J Respir Crit Care Med, Vol. 154, Issue 2 Pt 1, pp. 511-8, 1996 (PubMed).

Vesaluoma, Ylätupa, Mertaniemi et al.: "Increased release of tenascin in tear fluid after photorefractive keratectomy." in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Vol. 233, Issue 8, pp. 479-83, 1996 (PubMed).

Linnala, Kinnula, Laitinen et al.: "Transforming growth factor-beta regulates the expression of fibronectin and tenascin in BEAS 2B human bronchial epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 13, Issue 5, pp. 578-85, 1995 (PubMed).

Koukoulis, Gould, Bhattacharyya et al.: "Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: biologic and pathologic implications." in: Human pathology, Vol. 22, Issue 7, pp. 636-43, 1991 (PubMed).

Howeedy, Virtanen, Laitinen et al.: "Differential distribution of tenascin in the normal, hyperplastic, and neoplastic breast." in: Laboratory investigation, a journal of technical methods and pathology, Vol. 63, Issue 6, pp. 798-806, 1991 (PubMed).