Cathepsin K (CTSK) antibody

Antigen: Cathepsin K (CTSK)

Synonyms: CTSO, PKND, PYCD, CTS02, CTSO1, CTSO2, MGC23107, catK, Ms10q, MMS10-Q, AI323530, 26/29kD-proteinase, anon-SAGE:Wang-123, l(3)s3635, DmelCG8947, CG8947, CTSK, MGC134021, wu:fa95f03, wu:fb08b05, zgc:110367, ctso, pknd, pycd, cts02, ctso1, ctso2, MGC147539, OC-2, catk

Clonality: Monoclonal (3F9)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN108477

Additional Information

Alternative name: Cathepsin K

Format: Affinity-purified

Isotype: IgG2b  (Matching secondary antibodies)

Clone: 3F9

Description: Specification: Anti-Human Cathepsin K Mouse Monoclonal Antibody, Clone: 3F9 was raised in mouse against recombinant human Procathepsin K.

Synonyms: CTSO, PKND, PYCD, CTS02, CTSO1, CTSO2, MGC23107, catK, Ms10q, MMS10-Q, AI323530, 26/29kD-proteinase, anon-SAGE:Wang-123, l(3)s3635, DmelCG8947, CG8947, CTSK, MGC134021, wu:fa95f03, wu:fb08b05, zgc:110367, ctso, pknd, pycd, cts02, ctso1, ctso2, MGC147539, OC-2, catk

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Proteases

Restrictions: For Research Use only

Publications

Publications: Tepel C, Bromme D, Herzog V et al.: "Cathepsin K in thyroid epithelial cells: sequence, localization and possible function in extracellular proteolysis of thyroglobulin." in: J Cell Sci, Vol. 113 Pt 24, pp. 4487-98, 2000 (PubMed).

Chiellini C, Costa M, Novelli SE et al.: "Identification of cathepsin K as a novel marker of adiposity in white adipose tissue." in: J Cell Physiol, Vol. 195, Issue 2, pp. 309-21, 2003 (PubMed).

Dodds RA: "A cytochemical assay for osteoclast cathepsin K activity." in: Cell Biochem Funct, Vol. 21, Issue 3, pp. 231-4, 2003 (PubMed).