Complement Component 3 (C3) antibody

Antigen: Complement Component 3 (C3)

Synonyms: ASP, AHUS5, ARMD9, CPAMD1, Plp, AI255234, C3, cb26, sb:cb26, wu:fi34b03, wu:fj86e11, C3d, c3, MGC132248, asp, cpamd1

Clonality: Monoclonal (4H3)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN108480

Additional Information

Alternative name: Acylation Stimulating Protein (ASP)

Format: Affinity-purified

Isotype: IgG1  (Matching secondary antibodies)

Clone: 4H3

Description: Specification: Anti-Human Acylation Stimulating Protein (ASP) antibody, Clone: 4H3 is a mouse monoclonal antibody against human peptide with amino acid sequence RASHLGLA (which is located in C-terminal part of the human ASP).

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -40°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Restrictions: For Research Use only

Publications

Publications: Matthan NR, Cianflone K, Lichtenstein AH et al.: "Hydrogenated fat consumption affects acylation-stimulating protein levels and cholesterol esterification rates in moderately hypercholesterolemic women." in: J Lipid Res, Vol. 42, Issue 11, pp. 1841-8, 2001 (PubMed).

Faraj M, Havel PJ, Phelis S et al.: "Plasma acylation-stimulating protein, adiponectin, leptin, and ghrelin before and after weight loss induced by gastric bypass surgery in morbidly obese subjects." in: J Clin Endocrinol Metab, Vol. 88, Issue 4, pp. 1594-602, 2003 (PubMed).

Cianflone K, Phelis S, Davignon J et al.: "ApoE phenotype influences plasma ASP in hyperapoB subjects." in: Atherosclerosis, Vol. 170, Issue 2, pp. 285-91, 2003 (PubMed).