Leptin Receptor (LEPR) antibody

Antigen: Leptin Receptor (LEPR)

Synonyms: OBR, CD295, obr, cd295, ob-rb

Clonality: Monoclonal (LPR-02)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008, ISO 13485:2003

Catalog no.: ABIN108491

Additional Information

Alternative name: Leptin Receptor

Format: Protein G purified

Isotype: IgG1 kappa

Clone: LPR-02

Description: Specification: Anti-Human Leptin Receptor Antibody is a monoclonal antibody against recombinant human leptin receptor.

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Hormones, Receptors

Restrictions: For Research Use only

Publications

Tartaglia LA, Dembski M, Weng X et al.: "Identification and expression cloning of a leptin receptor, OB-R." in: Cell, Vol. 83, Issue 7, pp. 1263-71, 1995 (PubMed).

Cioffi JA, Shafer AW, Zupancic TJ et al.: "Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction." in: Nat Med, Vol. 2, Issue 5, pp. 585-9, 1996 (PubMed).

Campfield LA, Smith FJ, Burn P: "The OB protein (leptin) pathway--a link between adipose tissue mass and central neural networks." in: Horm Metab Res, Vol. 28, Issue 12, pp. 619-32, 1996 (PubMed).

Wang Y, Kuropatwinski KK, White DW et al.: "Leptin receptor action in hepatic cells." in: J Biol Chem, Vol. 272, Issue 26, pp. 16216-23, 1997 (PubMed).