Adiponectin, C1Q and Collagen Domain Containing (ADIPOQ) antibody

Antigen: Adiponectin, C1Q and Collagen Domain Containing (ADIPOQ)

Synonyms: ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, adiponectin, APN, Acdc, apM1, 30kDa, adipo, Acrp30, ADIPOQ, MGC138982, ADN, MGC84292

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN108503

Additional Information

Alternative name: Adiponectin

Format: Affinity-purified

Description: Specification: Anti-Murine Adiponectin antibody was raised in rabbit against recombinant Murine Adiponectin. Recombinant Murine Adiponectin is produced in HEK293 (Human embryonic kidney cell line). The recombinant Mouse Adiponectin is 100% homologous with the mouse serum adiponectin.

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Hormones

Restrictions: For Research Use only

Publications

Publications: Berg, Combs, Du et al.: "The adipocyte-secreted protein Acrp30 enhances hepatic insulin action." in: Nature medicine, Vol. 7, Issue 8, pp. 947-53, 2001 (PubMed).

Wang, Xu, Knight et al.: "Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity." in: The Journal of biological chemistry, Vol. 277, Issue 22, pp. 19521-9, 2002 (PubMed).

Yamauchi, Kamon, Minokoshi et al.: "Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase." in: Nature medicine, Vol. 8, Issue 11, pp. 1288-95, 2002 (PubMed).

Xu, Wang, Keshaw et al.: "The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice." in: The Journal of clinical investigation, Vol. 112, Issue 1, pp. 91-100, 2003 (PubMed).