Angiostatin (ANG) antibody

Antigen: Angiostatin (ANG)

Synonyms: DKFZp779M0222, Pg, AI649309, Ab1-346, PLG, LPA, wu:fb70e09, plg, DKFZp470G2422

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN108506

Additional Information

Alternative name: Angiostatin

Format: Affinity-purified

Description: Specification: Anti-Human Angiostatin Antibody was raised in rabbits against human serum angiostatin.

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Cytokines

Restrictions: For Research Use only

Publications

Publications: Sim BK, O'Reilly MS, Liang H et al.: "A recombinant human angiostatin protein inhibits experimental primary and metastatic cancer." in: Cancer Res, Vol. 57, Issue 7, pp. 1329-34, 1997 (PubMed).

Ji WR, Barrientos LG, Llinas M et al.: "Selective inhibition by kringle 5 of human plasminogen on endothelial cell migration, an important process in angiogenesis." in: Biochem Biophys Res Commun, Vol. 247, Issue 2, pp. 414-9, 1998 (PubMed).

Cao Y, Veitonmaki N, Keough K et al.: "Elevated levels of urine angiostatin and plasminogen/plasmin in cancer patients." in: Int J Mol Med, Vol. 5, Issue 5, pp. 547-51, 2000 (PubMed).

Shepard SR, Boucher R, Johnston J et al.: "Large-scale purification of recombinant human angiostatin." in: Protein Expr Purif, Vol. 20, Issue 2, pp. 216-27, 2000 (PubMed).