Cardiotrophin 1 (CTF1) antibody

Antigen: Cardiotrophin 1 (CTF1)

Synonyms: CT1, CT-1, CTF1, ct1, ct-1, ctf2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN108507

Additional Information

Alternative name: Cardiotrophin 1

Format: Affinity-purified

Description: Specification: Anti-Human Cardiotrophin-1 Antibody was raised in rabbits against recombinant human CT-1.

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Growth Factors

Restrictions: For Research Use only

Publications

Publications: Ghosh S, Ng LL, Talwar S et al.: "Cardiotrophin-1 protects the human myocardium from ischemic injury. Comparison with the first and second window of protection by ischemic preconditioning." in: Cardiovasc Res, Vol. 48, Issue 3, pp. 440-7, 2000 (PubMed).

Asai S, Saito Y, Kuwahara K et al.: "The heart is a source of circulating cardiotrophin-1 in humans." in: Biochem Biophys Res Commun, Vol. 279, Issue 2, pp. 320-3, 2000 (PubMed).

Talwar S, Squire IB, O'brien RJ et al.: "Plasma cardiotrophin-1 following acute myocardial infarction: relationship with left ventricular systolic dysfunction." in: Clin Sci (Lond), Vol. 102, Issue 1, pp. 9-14, 2002 (PubMed).

Shioji K, Kishimoto C, Nakamura H et al.: "Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity." in: Circulation, Vol. 106, Issue 11, pp. 1403-9, 2002 (PubMed).