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Collagen, Type XVIII, alpha 1 (COL18A1) antibody

Antigen

Collagen, Type XVIII, alpha 1 (COL18A1)

Synonyms KNO, KNO1, FLJ27325, FLJ34914, MGC74745, kno, MGC76284, COL18A1, MGC140499, endostatin, cb371, cb529, fc96d06, sb:cb529, wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
4 references available
Certificates ISO 9001:2008, ISO 13485:2003
Catalog no. ABIN108513
Quantity 0.1 mg
Price Product not available in this region.
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Additional Information

Alternative name Endostatin
Format Affinity-purified
Description Specification: Anti-Human Endostatin Antibody was raised in rabbit against recombinant human Endostatin. Recombinant Human Endostatin produced in Pichia pastoris is a single, glycosylated, polypeptide having a total molecular mass of 20,000 Dalton C-terminal fragment of collagen XVIII.

Application Details

Application Notes Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.
Storage Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.
Research Area Hormones
Restrictions For Research Use only

Publications

Rehn M, Pihlajaniemi T: "Alpha 1(XVIII), a collagen chain with frequent interruptions in the collagenous sequence, a distinct tissue distribution, and homology with type XV collagen." in: Proc Natl Acad Sci U S A, Vol. 91, Issue 10, pp. 4234-8, 1994 (PubMed).

O'Reilly MS, Boehm T, Shing Y et al.: "Endostatin: an endogenous inhibitor of angiogenesis and tumor growth." in: Cell, Vol. 88, Issue 2, pp. 277-85, 1997 (PubMed).

Sertie AL, Sossi V, Camargo AA et al.: "Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome)." in: Hum Mol Genet, Vol. 9, Issue 13, pp. 2051-8, 2000 (PubMed).

Karumanchi, Jha, Ramchandran et al.: "Cell surface glypicans are low-affinity endostatin receptors." in: Molecular cell, Vol. 7, Issue 4, pp. 811-22, 2001 (PubMed).

Alternatives

Alternatives for antigen "Collagen, Type XVIII, alpha 1 (COL18A1)", type "Antibodies"
Hosts Rabbit (46), Mouse (15), Rat (2), Goat (1)
Reactivities Human (56), Mouse (Murine) (28), Rat (Rattus) (19), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications ELISA (36), Western Blotting (WB) (33), Immunofluorescence (IF) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (IHC) (11), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunoprecipitation (IP) (2), Blocking Antibody (Inhibition) (1), Immunoassay (IA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (3), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (4), Center (2), Internal Region (1), N-Term (1)