Myostatin (MSTN) antibody

Antigen: Myostatin (MSTN)

Synonyms: GDF8, Cmpt, Gdf8, MGC124261, MGC124262, MGC124263, MSTN, GDF-8, gdf8, MGC109749, zgc:109749, NV13143, LOC100125998

Clonality: Polyclonal

Host: Bovine

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008, ISO 13485:2003

Catalog no.: ABIN108525

Additional Information

Alternative name: Myostatin

Format: Affinity-purified

Description: Specification: Anti-Human Myostatin Antibody was raised in bovine against Human Myostatin His-Tagged Fusion Protein. The amino acid sequence of the recombinant human Myostatin is 100% homologous to the amino acid sequence of the human Myostatin.

Application Details

Application Notes: Titre: Is defined by indirect ELISA, it is >1/100,000 for antibody concentration 1mg/ml, 25 ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve.

Storage: Store lyophilized antibody at 2-8°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Research Area: Hormones

Restrictions: For Research Use only

Publications

McPherron AC, Lee SJ: "Double muscling in cattle due to mutations in the myostatin gene." in: Proc Natl Acad Sci U S A, Vol. 94, Issue 23, pp. 12457-61, 1997 (PubMed).

Gonzalez-Cadavid NF, Taylor WE, Yarasheski K et al.: "Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting." in: Proc Natl Acad Sci U S A, Vol. 95, Issue 25, pp. 14938-43, 1998 (PubMed).

Sharma M, Kambadur R, Matthews KG et al.: "Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct." in: J Cell Physiol, Vol. 180, Issue 1, pp. 1-9, 1999 (PubMed).