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Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody

Details for Product No. ABIN108590, Supplier: Log in to see
Antigen
  • MGC53243
  • HNRPC
  • AL022939
  • D14Wsu171e
  • Hnrpc
  • Hnrpc1
  • Hnrpc2
  • hnRNPC1
  • hnRNPC2
  • hnrnp-C
  • bZ1G18.4
  • fb57h12
  • fi16b11
  • wu:fb57h12
  • wu:fi16b11
  • zgc:55701
  • C1
  • C2
  • HNRNP
  • SNRPC
  • hnRNP C
  • HNRNPC
Reactivity
Chicken, Hamster, Human, Monkey
74
41
36
9
4
4
4
2
2
2
1
Host
Mouse
70
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
60
31
28
20
16
11
6
6
2
1
1
1
Supplier
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Immunogen RNPs eluted from oligo (dT) cellulose column
Clone 4F4
Isotype IgG1
Specificity This antibody recognizes the two hnRNP C proteins of 41kDa (C1) and 43kDa (C2) in human cells, and corresponding proteins in monkey hamster &, chicken.
Characteristics Myeloma fusion partners:
SP2/0
Purification Protein A
Alternative Name hnRNP C1+C2 (HNRNPC Antibody Abstract)
Background Synonyms:
C1 antibody,C2 antibody,Heterogeneous nuclear ribonucleoprotein C antibody,Heterogeneous nuclearribonucleoproteins C1/C2 antibody,HNRNP antibody,hnRNP C1 / hnRNP C2 antibody,hnRNP C1/C2 antibody,hnRNPCantibody,HNRPC antibody,HNRPC_HUMAN antibody,MGC104306 antibody,MGC105117 antibody,MGC117353antibody,MGC131677 antibody,Nuclear ribonucleoprotein particle C1 protein antibody,Nuclear ribonucleoproteinparticle C2 protein antibody,SNRPC antibody
UniProt P07910
Pathways
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try around 1:100000 for western blot
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (ABIN108590) Western blot of hnRNP-C1/C2 on Hela extracts
 image for anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (ABIN108590) anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (Image 2)
Product cited in: Nicolas, Alazard-Dany, Biollay et al.: "Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments." in: Journal of virology, Vol. 84, Issue 17, pp. 8871-87, 2010 (PubMed).

Brunner, Ertel, Rozovics et al.: "Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins." in: Virology, Vol. 400, Issue 2, pp. 240-7, 2010 (PubMed).

Ertel, Brunner, Semler: "Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates." in: Journal of virology, Vol. 84, Issue 9, pp. 4229-42, 2010 (PubMed).

Mosessian, Avliyakulov, Mulholland et al.: "Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex." in: The Journal of biological chemistry, Vol. 284, Issue 44, pp. 30159-66, 2009 (PubMed).

Herrmann, Pably, Eckerich et al.: "Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 667-77, 2009 (PubMed).

Fu, Collins: "Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation." in: Molecular cell, Vol. 28, Issue 5, pp. 773-85, 2007 (PubMed).

Kuyumcu-Martinez, Wang, Cooper: "Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation." in: Molecular cell, Vol. 28, Issue 1, pp. 68-78, 2007 (PubMed).

Barrandon, Bonnet, Nguyen et al.: "The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes." in: Molecular and cellular biology, Vol. 27, Issue 20, pp. 6996-7006, 2007 (PubMed).

Baird, Lewis, Turcotte et al.: "A search for structurally similar cellular internal ribosome entry sites." in: Nucleic acids research, Vol. 35, Issue 14, pp. 4664-77, 2007 (PubMed).

Watson, Blanch, Lin et al.: "Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34096-103, 2006 (PubMed).

Lin, Yen: "A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein." in: RNA (New York, N.Y.), Vol. 12, Issue 8, pp. 1486-93, 2006 (PubMed).

Choi, Dreyfuss: "Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 23, pp. 7471-5, 1985 (PubMed).